Failure to oxygenate during cardiopulmonary bypass; treatment options and intervention algorithm

Membrane oxygenator failure remains a concern for perfusion teams. Successful outcomes for this low-frequency, high-risk intervention are predicated on having written institutional protocols for both the oxygenator change-out procedure as well as how often the procedure is practiced by staff perfusi...

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Bibliographic Details
Main Authors: Matte Gregory S., Regan William L., Gadille Sarah I., Connor Kevin R., Boyle Sharon L., Fynn-Thompson Francis E.
Format: Article
Language:English
Published: EDP Sciences 2024-12-01
Series:The Journal of ExtraCorporeal Technology
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Online Access:https://ject.edpsciences.org/articles/ject/full_html/2024/04/ject240028/ject240028.html
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Summary:Membrane oxygenator failure remains a concern for perfusion teams. Successful outcomes for this low-frequency, high-risk intervention are predicated on having written institutional protocols for both the oxygenator change-out procedure as well as how often the procedure is practiced by staff perfusionists. A recent review of peer-reviewed journal articles, textbooks and online resources revealed a lack of a unified intervention algorithm for failure to oxygenate during cardiopulmonary bypass (CPB). While an oxygenator change-out procedure may still be considered the gold standard for a confirmed device failure, temporizing measures exist that, in select cases, can afford time to the clinical team and even obviate the need for an oxygenator change-out procedure. We now consider the venous piggyback technique sourcing blood from the venous limb of the circuit a first-line intervention to afford enhanced patient safety while the clinical team decides on required interventions when oxygenator failure presents during CPB.
ISSN:0022-1058
2969-8960