ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks

Multimodal medical imaging of human pathological tissues provides comprehensive information to assist in clinical diagnosis. However, due to the high cost of imaging, physiological incompatibility, and the harmfulness of radioactive tracers, multimodal medical image data remains scarce. Currently, c...

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Main Authors: Liming Xu, Yanrong Lei, Bochuan Zheng, Jiancheng Lv, Weisheng Li
Format: Article
Language:English
Published: Tsinghua University Press 2024-12-01
Series:CAAI Artificial Intelligence Research
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Online Access:https://www.sciopen.com/article/10.26599/AIR.2024.9150035
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author Liming Xu
Yanrong Lei
Bochuan Zheng
Jiancheng Lv
Weisheng Li
author_facet Liming Xu
Yanrong Lei
Bochuan Zheng
Jiancheng Lv
Weisheng Li
author_sort Liming Xu
collection DOAJ
description Multimodal medical imaging of human pathological tissues provides comprehensive information to assist in clinical diagnosis. However, due to the high cost of imaging, physiological incompatibility, and the harmfulness of radioactive tracers, multimodal medical image data remains scarce. Currently, cross-modal medical synthesis methods can generate desired modal images from existing modal images. However, most existing methods are limited to specific domains. This paper proposes an Adaptive Domain Medical Image Synthesis Method based on Generative Adversarial Networks (ADGAN) to address this issue. ADGAN achieves multidirectional medical image synthesis and ensures pathological consistency by constructing a single generator to learn the latent shared representation of multiple domains. The generator employs dense connections in shallow layers to preserve edge details and incorporates auxiliary information in deep layers to retain pathological features. Additionally, spectral normalization is introduced into the discriminator to control discriminative performance and indirectly enhance the image synthesis ability of the generator. Theoretically, it can be proved that the proposed method can be trained quickly, and spectral normalization contributes to adaptive and multidirectional synthesis. In practice, comparing with recent state-of-the-art methods, ADGAN achieves average increments of 4.7% SSIM, 6.7% MSIM, 7.3% PSNR, and 9.2% VIF.
format Article
id doaj-art-49d05580422941faa285248cff2e3bb6
institution Kabale University
issn 2097-194X
2097-3691
language English
publishDate 2024-12-01
publisher Tsinghua University Press
record_format Article
series CAAI Artificial Intelligence Research
spelling doaj-art-49d05580422941faa285248cff2e3bb62025-01-10T06:44:32ZengTsinghua University PressCAAI Artificial Intelligence Research2097-194X2097-36912024-12-013915003510.26599/AIR.2024.9150035ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial NetworksLiming Xu0Yanrong Lei1Bochuan Zheng2Jiancheng Lv3Weisheng Li4School of Computer Science, China West Normal University, Nanchong 637002, ChinaSchool of Computer Science, China West Normal University, Nanchong 637002, ChinaSchool of Computer Science, China West Normal University, Nanchong 637002, ChinaCollege of Computer Science and Technology, Sichuan University, Chengdu 130012, ChinaCollege of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing 400065, ChinaMultimodal medical imaging of human pathological tissues provides comprehensive information to assist in clinical diagnosis. However, due to the high cost of imaging, physiological incompatibility, and the harmfulness of radioactive tracers, multimodal medical image data remains scarce. Currently, cross-modal medical synthesis methods can generate desired modal images from existing modal images. However, most existing methods are limited to specific domains. This paper proposes an Adaptive Domain Medical Image Synthesis Method based on Generative Adversarial Networks (ADGAN) to address this issue. ADGAN achieves multidirectional medical image synthesis and ensures pathological consistency by constructing a single generator to learn the latent shared representation of multiple domains. The generator employs dense connections in shallow layers to preserve edge details and incorporates auxiliary information in deep layers to retain pathological features. Additionally, spectral normalization is introduced into the discriminator to control discriminative performance and indirectly enhance the image synthesis ability of the generator. Theoretically, it can be proved that the proposed method can be trained quickly, and spectral normalization contributes to adaptive and multidirectional synthesis. In practice, comparing with recent state-of-the-art methods, ADGAN achieves average increments of 4.7% SSIM, 6.7% MSIM, 7.3% PSNR, and 9.2% VIF.https://www.sciopen.com/article/10.26599/AIR.2024.9150035generative adversarial networksmultimodal medical imagesadaptive domainlatent shared representation
spellingShingle Liming Xu
Yanrong Lei
Bochuan Zheng
Jiancheng Lv
Weisheng Li
ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks
CAAI Artificial Intelligence Research
generative adversarial networks
multimodal medical images
adaptive domain
latent shared representation
title ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks
title_full ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks
title_fullStr ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks
title_full_unstemmed ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks
title_short ADGAN: Adaptive Domain Medical Image Synthesis Based on Generative Adversarial Networks
title_sort adgan adaptive domain medical image synthesis based on generative adversarial networks
topic generative adversarial networks
multimodal medical images
adaptive domain
latent shared representation
url https://www.sciopen.com/article/10.26599/AIR.2024.9150035
work_keys_str_mv AT limingxu adganadaptivedomainmedicalimagesynthesisbasedongenerativeadversarialnetworks
AT yanronglei adganadaptivedomainmedicalimagesynthesisbasedongenerativeadversarialnetworks
AT bochuanzheng adganadaptivedomainmedicalimagesynthesisbasedongenerativeadversarialnetworks
AT jianchenglv adganadaptivedomainmedicalimagesynthesisbasedongenerativeadversarialnetworks
AT weishengli adganadaptivedomainmedicalimagesynthesisbasedongenerativeadversarialnetworks