Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program.
<h4>Background</h4>Although moderate and severe Covid-19 patients have shown obstructive and restrictive disorders in pulmonary function after recovery from the disease, studies evaluating the effectiveness of rehabilitation programs that seek to improve lung function are scarce.<h4&g...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0300826 |
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| author | Carlos D Páez-Mora Diana Carolina Zona Teddy Angarita-Sierra Matilde E Rojas-Paredes Daniela Cano-Trejos |
| author_facet | Carlos D Páez-Mora Diana Carolina Zona Teddy Angarita-Sierra Matilde E Rojas-Paredes Daniela Cano-Trejos |
| author_sort | Carlos D Páez-Mora |
| collection | DOAJ |
| description | <h4>Background</h4>Although moderate and severe Covid-19 patients have shown obstructive and restrictive disorders in pulmonary function after recovery from the disease, studies evaluating the effectiveness of rehabilitation programs that seek to improve lung function are scarce.<h4>Aim</h4>Herein, we evaluate changes in lung function and perceived dyspnea in Covid-19 patients after undergoing 12 weeks of a pulmonary rehabilitation (PR) program.<h4>Design</h4>Retrospective observational study.<h4>Setting</h4>Cesar, Colombia Neumocesar Pneumological Center.<h4>Population</h4>100 outpatients with a history of Covid-19.<h4>Methods</h4>Respiratory function using spirometry parameters, as well as perceived dyspnea, measured by the modified Medical Research Council (mMRC) dyspnea scale, was evaluated in 100 patients with a history of Covid-19. We used univariate and multivariate statistical approaches to assess changes in lung function and perceived dyspnea before and after a PR program to determine whether gender, age, height, weight, comorbidities, and oxygen delivery system affects the recovery of lung function and perceived dyspnea.<h4>Results</h4>It was found that PR treatment has positive effects on respiratory pathologies caused by SARS-CoV-2 infection regardless of patient gender (S = 0,029), indicating that rehabilitation provided benefits regardless of the physical characteristics of the patients. Both univariate and multivariate statistical analyses indicated that FVC (P = 0,0001), FEV1(P = 0,0001), and mMRC (P = 0,0001) are robust diagnostic indicators of lung function recovery and perceived dyspnea. Both invasive and non-invasive positive pressure ventilatory support had deleterious effects on lung function prolongating patient recovery (P = 0,0001).<h4>Conclusions</h4>Rehabilitation programs can benefit patients facing respiratory pathologies caused by SARS-CoV-2 infection. Additional research on the long-term effects of the sequelae of Covid-19 is needed.<h4>Clinical rehabilitation impact</h4>PR programs have positive effects on patients facing respiratory pathologies caused by SARS-CoV-2 infection. |
| format | Article |
| id | doaj-art-49b81677c1694db1b6069d9f3ba9293a |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-49b81677c1694db1b6069d9f3ba9293a2024-12-10T05:31:53ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011911e030082610.1371/journal.pone.0300826Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program.Carlos D Páez-MoraDiana Carolina ZonaTeddy Angarita-SierraMatilde E Rojas-ParedesDaniela Cano-Trejos<h4>Background</h4>Although moderate and severe Covid-19 patients have shown obstructive and restrictive disorders in pulmonary function after recovery from the disease, studies evaluating the effectiveness of rehabilitation programs that seek to improve lung function are scarce.<h4>Aim</h4>Herein, we evaluate changes in lung function and perceived dyspnea in Covid-19 patients after undergoing 12 weeks of a pulmonary rehabilitation (PR) program.<h4>Design</h4>Retrospective observational study.<h4>Setting</h4>Cesar, Colombia Neumocesar Pneumological Center.<h4>Population</h4>100 outpatients with a history of Covid-19.<h4>Methods</h4>Respiratory function using spirometry parameters, as well as perceived dyspnea, measured by the modified Medical Research Council (mMRC) dyspnea scale, was evaluated in 100 patients with a history of Covid-19. We used univariate and multivariate statistical approaches to assess changes in lung function and perceived dyspnea before and after a PR program to determine whether gender, age, height, weight, comorbidities, and oxygen delivery system affects the recovery of lung function and perceived dyspnea.<h4>Results</h4>It was found that PR treatment has positive effects on respiratory pathologies caused by SARS-CoV-2 infection regardless of patient gender (S = 0,029), indicating that rehabilitation provided benefits regardless of the physical characteristics of the patients. Both univariate and multivariate statistical analyses indicated that FVC (P = 0,0001), FEV1(P = 0,0001), and mMRC (P = 0,0001) are robust diagnostic indicators of lung function recovery and perceived dyspnea. Both invasive and non-invasive positive pressure ventilatory support had deleterious effects on lung function prolongating patient recovery (P = 0,0001).<h4>Conclusions</h4>Rehabilitation programs can benefit patients facing respiratory pathologies caused by SARS-CoV-2 infection. Additional research on the long-term effects of the sequelae of Covid-19 is needed.<h4>Clinical rehabilitation impact</h4>PR programs have positive effects on patients facing respiratory pathologies caused by SARS-CoV-2 infection.https://doi.org/10.1371/journal.pone.0300826 |
| spellingShingle | Carlos D Páez-Mora Diana Carolina Zona Teddy Angarita-Sierra Matilde E Rojas-Paredes Daniela Cano-Trejos Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program. PLoS ONE |
| title | Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program. |
| title_full | Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program. |
| title_fullStr | Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program. |
| title_full_unstemmed | Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program. |
| title_short | Changes in lung function and dyspnea perception in Colombian Covid-19 patients after a 12-week pulmonary rehabilitation program. |
| title_sort | changes in lung function and dyspnea perception in colombian covid 19 patients after a 12 week pulmonary rehabilitation program |
| url | https://doi.org/10.1371/journal.pone.0300826 |
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