Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant
Sargassum polycystum is a brown seaweed with potential antioxidant properties due to its bioactive components. These bioactive components can be altered through biotransformation by fermentation. This fermentation can be carried out using marine endophytic fungi. The purpose of this study is to dete...
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EDP Sciences
2024-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2024/66/bioconf_eafta2024_01010.pdf |
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| author | Nur Haliza Ghea Dyah Hardiningtyas Safrina Tarman Kustiariyah |
| author_facet | Nur Haliza Ghea Dyah Hardiningtyas Safrina Tarman Kustiariyah |
| author_sort | Nur Haliza Ghea |
| collection | DOAJ |
| description | Sargassum polycystum is a brown seaweed with potential antioxidant properties due to its bioactive components. These bioactive components can be altered through biotransformation by fermentation. This fermentation can be carried out using marine endophytic fungi. The purpose of this study is to determine effect of fermentation process using the marine endophytic fungi Trichoderma harzianum KTR3 and KTR4 on the bioactive components and antioxidant activity. Sargassum polycystum and fermented Sargassum polycstum will be macerated using ethyl acetate solvent for 72 hours. Sargassum polycstum extract and Sargassum polycstum fermented with KTR3 and KTR4 showed the presence of tannins, saponins, steroids, and terpenoids. Fermentation treatment with Trichoderma harzianum KTR3 resulted a non-significant increase in antioxidant activity, indicated by a decrease in IC50 values in the fermented Sargassum polycstum extract. Metabolite profiling revealed an increase in the composition of compounds in Sargassum polycstum fermented with the KTR3 isolate, identifying 52 compounds, of which 36 were new biotransformation products. Marker compounds in fermented Sargassum polycstum extract are citrinin and pheophorbide A. |
| format | Article |
| id | doaj-art-49aac3a95be44aa7b451bc4b2d64d6ba |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-49aac3a95be44aa7b451bc4b2d64d6ba2025-01-16T11:19:24ZengEDP SciencesBIO Web of Conferences2117-44582024-01-011470101010.1051/bioconf/202414701010bioconf_eafta2024_01010Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidantNur Haliza Ghea0Dyah Hardiningtyas Safrina1Tarman Kustiariyah2Department of Aquatic Product Technology, Faculty of Fisheries and Marine Science, IPB UniversityDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Science, IPB UniversityDepartment of Aquatic Product Technology, Faculty of Fisheries and Marine Science, IPB UniversitySargassum polycystum is a brown seaweed with potential antioxidant properties due to its bioactive components. These bioactive components can be altered through biotransformation by fermentation. This fermentation can be carried out using marine endophytic fungi. The purpose of this study is to determine effect of fermentation process using the marine endophytic fungi Trichoderma harzianum KTR3 and KTR4 on the bioactive components and antioxidant activity. Sargassum polycystum and fermented Sargassum polycstum will be macerated using ethyl acetate solvent for 72 hours. Sargassum polycstum extract and Sargassum polycstum fermented with KTR3 and KTR4 showed the presence of tannins, saponins, steroids, and terpenoids. Fermentation treatment with Trichoderma harzianum KTR3 resulted a non-significant increase in antioxidant activity, indicated by a decrease in IC50 values in the fermented Sargassum polycstum extract. Metabolite profiling revealed an increase in the composition of compounds in Sargassum polycstum fermented with the KTR3 isolate, identifying 52 compounds, of which 36 were new biotransformation products. Marker compounds in fermented Sargassum polycstum extract are citrinin and pheophorbide A.https://www.bio-conferences.org/articles/bioconf/pdf/2024/66/bioconf_eafta2024_01010.pdf |
| spellingShingle | Nur Haliza Ghea Dyah Hardiningtyas Safrina Tarman Kustiariyah Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant BIO Web of Conferences |
| title | Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant |
| title_full | Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant |
| title_fullStr | Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant |
| title_full_unstemmed | Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant |
| title_short | Biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant |
| title_sort | biotransformation of bioactive compounds in seaweed through fermentation with marine endophytic fungi as antioxidant |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2024/66/bioconf_eafta2024_01010.pdf |
| work_keys_str_mv | AT nurhalizaghea biotransformationofbioactivecompoundsinseaweedthroughfermentationwithmarineendophyticfungiasantioxidant AT dyahhardiningtyassafrina biotransformationofbioactivecompoundsinseaweedthroughfermentationwithmarineendophyticfungiasantioxidant AT tarmankustiariyah biotransformationofbioactivecompoundsinseaweedthroughfermentationwithmarineendophyticfungiasantioxidant |