Inhibition of the polyol pathway by Ducrosia anethifolia extract: plausible implications for diabetic retinopathy treatment

Inhibition of the polyol pathway by Ducrosia anethifolia extract: plausible implications for diabetic retinopathy treatment

IntroductionDiabetic retinopathy is a significant microvascular disorder and the leading cause of vision impairment in working-age individuals. Hyperglycemia triggers retinal damage through mechanisms such as the polyol pathway and the accumulation of advanced glycation end products (AGEs). Inhibiti...

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Bibliographic Details
Main Authors:	Saheem Ahmad, Mohammad Faizan Ali Ahmad, Saif Khan, Sultan Alouffi, Mahvish Khan, Mohd Wajid Ali Khan, Irfan Ahmad Ansari
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Pharmacology
Subjects:	diabetic retinopathy polyol pathway advanced glycation end products (AGEs) aldose reductase (AR) sorbitol dehydrogenase (SD)
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1513967/full
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