Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian
Abstract This study aimed to translate and validate the Functional Assessment of Cancer Therapy – Head & Neck (FACT-HN) in a Serbian-speaking population, assessing its psychometric properties and utility in evaluating the quality of life in head and neck cancer patients. The research focuses on...
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Nature Portfolio
2025-01-01
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| Online Access: | https://doi.org/10.1038/s41598-024-83246-1 |
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| author | Masa Petrovic Bojana Salovic Ana Tomic Tanja Jesic-Petrovic Aleksandar Matejic Ivana Radovic Silvana Babic Aleksa Korugic Drago Jelovac Nikola Mikovic Sasa Jakovljevic Svetislav Pelemis Milovan Dimitrijevic Jovica Milovanovic Ana Jotic Aleksandar Trivic Ana Dimitrijevic Sulin Bulatovic Zoran Dudvarski Ivan Soldatovic Jelena Ilic-Zivojinovic |
| author_facet | Masa Petrovic Bojana Salovic Ana Tomic Tanja Jesic-Petrovic Aleksandar Matejic Ivana Radovic Silvana Babic Aleksa Korugic Drago Jelovac Nikola Mikovic Sasa Jakovljevic Svetislav Pelemis Milovan Dimitrijevic Jovica Milovanovic Ana Jotic Aleksandar Trivic Ana Dimitrijevic Sulin Bulatovic Zoran Dudvarski Ivan Soldatovic Jelena Ilic-Zivojinovic |
| author_sort | Masa Petrovic |
| collection | DOAJ |
| description | Abstract This study aimed to translate and validate the Functional Assessment of Cancer Therapy – Head & Neck (FACT-HN) in a Serbian-speaking population, assessing its psychometric properties and utility in evaluating the quality of life in head and neck cancer patients. The research focuses on determining the translated questionnaire’s reliability, validity, and cultural relevance. A total of 106 Serbian-speaking head and neck cancer patients completed the translated FACT-HN, along with other validated instruments, including the EORTC QLQ-C30, EORTC QLQ-HN43, CES-D, and GAD-7. The translation followed a standard internationally accepted procedure. Psychometric analyses were conducted using confirmatory and exploratory factor analysis, Pearson correlations, and reliability measures such as Cronbach’s alpha and intraclass correlation coefficients. The Serbian version of the FACT-HN showed excellent internal consistency across all subscales, with Cronbach’s alpha ranging from 0.70 to 0.89. Confirmatory factor analysis confirmed the five-factor structure. Strong correlations were observed between the FACT-HN and other validated QoL measures, particularly with the EORTC QLQ-C30 and EORTC QLQ-HN43. Convergent validity was satisfactory for all components except the Social Well-Being component. The Serbian version of the FACT-HN is a valid and reliable tool for assessing the quality of life in head and neck cancer patients. It provides a comprehensive assessment of physical, social, emotional, and functional well-being, making it valuable for clinical and research applications in Serbian-speaking populations. Further research is needed to assess its sensitivity to longitudinal treatment-related changes. |
| format | Article |
| id | doaj-art-49492ceebd8d492dbd3b82a63a238e3f |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-49492ceebd8d492dbd3b82a63a238e3f2025-01-05T12:16:12ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-024-83246-1Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in SerbianMasa Petrovic0Bojana Salovic1Ana Tomic2Tanja Jesic-Petrovic3Aleksandar Matejic4Ivana Radovic5Silvana Babic6Aleksa Korugic7Drago Jelovac8Nikola Mikovic9Sasa Jakovljevic10Svetislav Pelemis11Milovan Dimitrijevic12Jovica Milovanovic13Ana Jotic14Aleksandar Trivic15Ana Dimitrijevic16Sulin Bulatovic17Zoran Dudvarski18Ivan Soldatovic19Jelena Ilic-Zivojinovic20Institute for Cardiovascular Diseases “Dedinje”Faculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradePublic Health Care Center DobojFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeClinic of Maxillofacial Surgery, School of Dental Medicine, University of BelgradeClinic of Maxillofacial Surgery, School of Dental Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, University of BelgradeFaculty of Medicine, Institute for Medical Statistics and Informatics, University of BelgrdeFaculty of Medicine, Institute of Hygiene and Medical Ecology, University of BelgradeAbstract This study aimed to translate and validate the Functional Assessment of Cancer Therapy – Head & Neck (FACT-HN) in a Serbian-speaking population, assessing its psychometric properties and utility in evaluating the quality of life in head and neck cancer patients. The research focuses on determining the translated questionnaire’s reliability, validity, and cultural relevance. A total of 106 Serbian-speaking head and neck cancer patients completed the translated FACT-HN, along with other validated instruments, including the EORTC QLQ-C30, EORTC QLQ-HN43, CES-D, and GAD-7. The translation followed a standard internationally accepted procedure. Psychometric analyses were conducted using confirmatory and exploratory factor analysis, Pearson correlations, and reliability measures such as Cronbach’s alpha and intraclass correlation coefficients. The Serbian version of the FACT-HN showed excellent internal consistency across all subscales, with Cronbach’s alpha ranging from 0.70 to 0.89. Confirmatory factor analysis confirmed the five-factor structure. Strong correlations were observed between the FACT-HN and other validated QoL measures, particularly with the EORTC QLQ-C30 and EORTC QLQ-HN43. Convergent validity was satisfactory for all components except the Social Well-Being component. The Serbian version of the FACT-HN is a valid and reliable tool for assessing the quality of life in head and neck cancer patients. It provides a comprehensive assessment of physical, social, emotional, and functional well-being, making it valuable for clinical and research applications in Serbian-speaking populations. Further research is needed to assess its sensitivity to longitudinal treatment-related changes.https://doi.org/10.1038/s41598-024-83246-1TranslationValidationFACTHNHead and Neck CancerQuality of Life |
| spellingShingle | Masa Petrovic Bojana Salovic Ana Tomic Tanja Jesic-Petrovic Aleksandar Matejic Ivana Radovic Silvana Babic Aleksa Korugic Drago Jelovac Nikola Mikovic Sasa Jakovljevic Svetislav Pelemis Milovan Dimitrijevic Jovica Milovanovic Ana Jotic Aleksandar Trivic Ana Dimitrijevic Sulin Bulatovic Zoran Dudvarski Ivan Soldatovic Jelena Ilic-Zivojinovic Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian Scientific Reports Translation Validation FACTHN Head and Neck Cancer Quality of Life |
| title | Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian |
| title_full | Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian |
| title_fullStr | Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian |
| title_full_unstemmed | Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian |
| title_short | Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian |
| title_sort | functional assessment of cancer therapy head neck fact hn translation and validation in serbian |
| topic | Translation Validation FACTHN Head and Neck Cancer Quality of Life |
| url | https://doi.org/10.1038/s41598-024-83246-1 |
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