Superficial acral fibromyxoma on the palm: a case report

Abstract Background Superficial acral fibromyxoma is a noncancerous, benign tumor of soft tissue with an unidentified origin. Occurrences of abnormalities on the palm are less frequently documented. Case report presentation A 47-year-old East Asian woman presented with a palm tumor on her left knuck...

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Main Authors: Chunli Yang, Bin Lu, Zheng Lin
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s13256-024-05020-1
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author Chunli Yang
Bin Lu
Zheng Lin
author_facet Chunli Yang
Bin Lu
Zheng Lin
author_sort Chunli Yang
collection DOAJ
description Abstract Background Superficial acral fibromyxoma is a noncancerous, benign tumor of soft tissue with an unidentified origin. Occurrences of abnormalities on the palm are less frequently documented. Case report presentation A 47-year-old East Asian woman presented with a palm tumor on her left knuckle that had been present for 4 months. Four months prior to treatment, a reddish nodule appeared at the site due to continuous friction, but the patient did not pay attention to it. Upon physical examination, a pale-reddish nodule measuring approximately 0.8 × 0.8 cm was observed on the flexion side of the fourth metacarpophalangeal joint of the left hand. The nodule was nearly round, exhibited distinct margins, featured slight surface keratosis, and displayed a collar-like alteration at its periphery. The stroma showed significant fibrous proliferation and a myxoid matrix. The cellular composition consisted primarily of spindle-shaped fibroblasts, which were locally arranged in bundles within the stroma. Sparse slender blood vessels were distributed along with observed red blood cell extravasation. Immunohistochemistry of the tumor showed CD34 (+), CD99 (−), desmin (−), epithelial membrane antigen (−). Extensive resection of the mass was performed. Conclusion A rounded mass on the palm of the hand may be superficial acral fibromyxoma. The optimal approach for treating superficial acral fibromyxoma involves complete surgical removal of the mass followed by postoperative monitoring.
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spelling doaj-art-490f34eef75b404790c930d7d028d17d2025-01-12T12:25:27ZengBMCJournal of Medical Case Reports1752-19472025-01-011911410.1186/s13256-024-05020-1Superficial acral fibromyxoma on the palm: a case reportChunli Yang0Bin Lu1Zheng Lin2Department of Clinical Medicine, Jining Medical UniversityDepartment of Clinical Medicine, Jining Medical UniversityDepartment of Clinical Medicine, Jining Medical UniversityAbstract Background Superficial acral fibromyxoma is a noncancerous, benign tumor of soft tissue with an unidentified origin. Occurrences of abnormalities on the palm are less frequently documented. Case report presentation A 47-year-old East Asian woman presented with a palm tumor on her left knuckle that had been present for 4 months. Four months prior to treatment, a reddish nodule appeared at the site due to continuous friction, but the patient did not pay attention to it. Upon physical examination, a pale-reddish nodule measuring approximately 0.8 × 0.8 cm was observed on the flexion side of the fourth metacarpophalangeal joint of the left hand. The nodule was nearly round, exhibited distinct margins, featured slight surface keratosis, and displayed a collar-like alteration at its periphery. The stroma showed significant fibrous proliferation and a myxoid matrix. The cellular composition consisted primarily of spindle-shaped fibroblasts, which were locally arranged in bundles within the stroma. Sparse slender blood vessels were distributed along with observed red blood cell extravasation. Immunohistochemistry of the tumor showed CD34 (+), CD99 (−), desmin (−), epithelial membrane antigen (−). Extensive resection of the mass was performed. Conclusion A rounded mass on the palm of the hand may be superficial acral fibromyxoma. The optimal approach for treating superficial acral fibromyxoma involves complete surgical removal of the mass followed by postoperative monitoring.https://doi.org/10.1186/s13256-024-05020-1Superficial acral fibromyxomaPalmSkin tutorCase report
spellingShingle Chunli Yang
Bin Lu
Zheng Lin
Superficial acral fibromyxoma on the palm: a case report
Journal of Medical Case Reports
Superficial acral fibromyxoma
Palm
Skin tutor
Case report
title Superficial acral fibromyxoma on the palm: a case report
title_full Superficial acral fibromyxoma on the palm: a case report
title_fullStr Superficial acral fibromyxoma on the palm: a case report
title_full_unstemmed Superficial acral fibromyxoma on the palm: a case report
title_short Superficial acral fibromyxoma on the palm: a case report
title_sort superficial acral fibromyxoma on the palm a case report
topic Superficial acral fibromyxoma
Palm
Skin tutor
Case report
url https://doi.org/10.1186/s13256-024-05020-1
work_keys_str_mv AT chunliyang superficialacralfibromyxomaonthepalmacasereport
AT binlu superficialacralfibromyxomaonthepalmacasereport
AT zhenglin superficialacralfibromyxomaonthepalmacasereport