A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii)
Abstract Tibetan antelope (Pantholops hodgsonii), a wild ruminant endemic to the Qinghai-Tibetan Plateau (QTP) in China, has evolved a series of genetic and physiological adaptation strategies to thrive in the harsh plateau environments. However, limited research on the genome of this species exists...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-11-01
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| Series: | Scientific Data |
| Online Access: | https://doi.org/10.1038/s41597-024-04089-z |
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| author | Bo Xu Jiarui Chen Pengfei Song Haifeng Gu Feng Jiang Bin Li Qing Wei Tongzuo Zhang |
| author_facet | Bo Xu Jiarui Chen Pengfei Song Haifeng Gu Feng Jiang Bin Li Qing Wei Tongzuo Zhang |
| author_sort | Bo Xu |
| collection | DOAJ |
| description | Abstract Tibetan antelope (Pantholops hodgsonii), a wild ruminant endemic to the Qinghai-Tibetan Plateau (QTP) in China, has evolved a series of genetic and physiological adaptation strategies to thrive in the harsh plateau environments. However, limited research on the genome of this species exists. Here, we established a high-quality chromosome-level reference genome assembly of the Tibetan antelope using PacBio HiFi, DNBSEQ, and Hi-C sequencing data. The assembly, totaling 3.13 GB, consists of 31 chromosomes (29 + X + partial Y), with a Scaffold N50 length of 92.23 Mb. The quality value (QV) and Benchmarking Universal Single-Copy Ortholog (BUSCO) score were 70.14 and 98.20%, respectively, indicating that our genome sequence is of high quality and completeness. Our genome not only contribute to the genetic conservation of Tibetan antelope but also provides a valuable resource for genetic, ecological, and evolutionary research within the sub-family Caprinae. |
| format | Article |
| id | doaj-art-48e63728abd04992873f889b1beb089f |
| institution | Kabale University |
| issn | 2052-4463 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Data |
| spelling | doaj-art-48e63728abd04992873f889b1beb089f2024-11-17T12:09:01ZengNature PortfolioScientific Data2052-44632024-11-011111710.1038/s41597-024-04089-zA high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii)Bo Xu0Jiarui Chen1Pengfei Song2Haifeng Gu3Feng Jiang4Bin Li5Qing Wei6Tongzuo Zhang7Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesCollege of Ecological and Environmental Engineering, Qinghai University 10743Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesKey Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesKey Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesKey Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesCollege of Ecological and Environmental Engineering, Qinghai University 10743Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of SciencesAbstract Tibetan antelope (Pantholops hodgsonii), a wild ruminant endemic to the Qinghai-Tibetan Plateau (QTP) in China, has evolved a series of genetic and physiological adaptation strategies to thrive in the harsh plateau environments. However, limited research on the genome of this species exists. Here, we established a high-quality chromosome-level reference genome assembly of the Tibetan antelope using PacBio HiFi, DNBSEQ, and Hi-C sequencing data. The assembly, totaling 3.13 GB, consists of 31 chromosomes (29 + X + partial Y), with a Scaffold N50 length of 92.23 Mb. The quality value (QV) and Benchmarking Universal Single-Copy Ortholog (BUSCO) score were 70.14 and 98.20%, respectively, indicating that our genome sequence is of high quality and completeness. Our genome not only contribute to the genetic conservation of Tibetan antelope but also provides a valuable resource for genetic, ecological, and evolutionary research within the sub-family Caprinae.https://doi.org/10.1038/s41597-024-04089-z |
| spellingShingle | Bo Xu Jiarui Chen Pengfei Song Haifeng Gu Feng Jiang Bin Li Qing Wei Tongzuo Zhang A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii) Scientific Data |
| title | A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii) |
| title_full | A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii) |
| title_fullStr | A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii) |
| title_full_unstemmed | A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii) |
| title_short | A high-quality chromosome-level reference genome assembly of Tibetan antelope (Pantholops hodgsonii) |
| title_sort | high quality chromosome level reference genome assembly of tibetan antelope pantholops hodgsonii |
| url | https://doi.org/10.1038/s41597-024-04089-z |
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