Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms

Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms

Abstract Background Osteoporosis significantly increases the risk of vertebral fractures, particularly among postmenopausal women, decreasing their quality of life. These fractures, often undiagnosed, can lead to severe health consequences and are influenced by bone mineral density and abnormal load...

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Main Authors: Yi-Chou Chen, Hui-Chen Su, Shih-Ming Huang, Ching-Hsiao Yu, Jen-Huei Chang, Yi-Lin Chiu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BioData Mining
Subjects:
Osteoporosis
Vertebral fractures
XGBoost
Th17 cell differentiation
Online Access:https://doi.org/10.1186/s13040-025-00427-y
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