Construction and screening of L-valine high-yielding Escherichia coli using an artificial screening marker

Construction and screening of L-valine high-yielding Escherichia coli using an artificial screening marker

IntroductionL-valine is commonly utilized in cosmetics, pharmaceuticals, food additives, and animal feeds. The selection and breeding of high-yielding, low-cost, and genetically stable production strains have become a key objective in the L-valine production industry.MethodsUsing Escherichia coli DB...

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Bibliographic Details
Main Authors: Bowen Du, Sheng Gao, Daixue Kou, Yinuo Li, Dan Li, Yongsheng Cao, Cuiping Yang, Chuanzhuang Guo, Jianbin Wang, Junqing Wang, Nan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
high-throughput screening
rare codon
L-valine
fluorescent protein
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1627242/full
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