DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two a...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/8503275 |
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| author | B. Dhakal A. D’Souza M. Pasquini W. Saber T. S. Fenske R. B. Moss W. R. Drobyski P. Hari M. Z. Abidi |
| author_facet | B. Dhakal A. D’Souza M. Pasquini W. Saber T. S. Fenske R. B. Moss W. R. Drobyski P. Hari M. Z. Abidi |
| author_sort | B. Dhakal |
| collection | DOAJ |
| description | Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure. |
| format | Article |
| id | doaj-art-488ac97cd4e94dbaba27c7f54c24623a |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-488ac97cd4e94dbaba27c7f54c24623a2025-02-03T05:47:16ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/85032758503275DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical VentilationB. Dhakal0A. D’Souza1M. Pasquini2W. Saber3T. S. Fenske4R. B. Moss5W. R. Drobyski6P. Hari7M. Z. Abidi8Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USADivision of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USADivision of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USADivision of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USADivision of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USAAnsun BioPharma, San Diego, CA 92121, USADivision of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USADivision of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USADivision of Infectious Disease, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USAParainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure.http://dx.doi.org/10.1155/2016/8503275 |
| spellingShingle | B. Dhakal A. D’Souza M. Pasquini W. Saber T. S. Fenske R. B. Moss W. R. Drobyski P. Hari M. Z. Abidi DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation Case Reports in Medicine |
| title | DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation |
| title_full | DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation |
| title_fullStr | DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation |
| title_full_unstemmed | DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation |
| title_short | DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation |
| title_sort | das181 treatment of severe parainfluenza virus 3 pneumonia in allogeneic hematopoietic stem cell transplant recipients requiring mechanical ventilation |
| url | http://dx.doi.org/10.1155/2016/8503275 |
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