Geographic Influence and Metabolomics-Driven Discovery of 5-Alpha Reductase Inhibitors in <i>Tectona grandis</i> L.f. (Teak) Leaves

Geographic Influence and Metabolomics-Driven Discovery of 5-Alpha Reductase Inhibitors in <i>Tectona grandis</i> L.f. (Teak) Leaves

The inhibition of steroid 5-alpha reductase (S5AR), a key mechanism for managing dihydrotestosterone-dependent conditions, has been demonstrated in teak (<i>Tectona grandis</i> L.f.) leaf extracts. Our recent clinical study confirmed the effectiveness of a hair growth formulation contain...

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Main Authors: Nutchaninad Tanuphol, Corine Girard, Prapapan Temkitthawon, Nungruthai Suphrom, Nitra Nuengchamnong, Tongchai Saesong, Kamonlak Insumrong, Abdulaziz Wadeng, Wiyada Khangkhachit, Andy Zedet, Ratchadaree Intayot, Siriporn Jungsuttiwong, Anuchit Plubrukarn, Francois Senejoux, Kornkanok Ingkaninan
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
<i>Tectona grandis</i> L.f.
steroid 5-alpha reductase inhibitor
metabolomics
structure elucidation
Online Access:https://www.mdpi.com/1420-3049/30/14/2895
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