Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway

Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway

Summary: MCFD2 and ERGIC-53 form a cargo receptor complex that plays a crucial role in transporting specific glycoproteins, including blood coagulation factor VIII, from the endoplasmic reticulum to the Golgi apparatus. We have demonstrated that MCFD2 recognizes a 10-amino-acid sequence in factor VI...

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Bibliographic Details
Main Authors: Hirokazu Yagi, Rino Yamada, Taiki Saito, Rena Honda, Rio Nakano, Kengo Inutsuka, Seigo Tateo, Hideo Kusano, Kumiko Nishimura, Saeko Yanaka, Takuro Tojima, Akihiko Nakano, Jun-ichi Furukawa, Maho Yagi-Utsumi, Shungo Adachi, Koichi Kato
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Biochemistry
Protein
Properties of biomolecules
Glycobiology
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026841
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