EMT-related cell-matrix interactions are linked to states of cell unjamming in cancer spheroid invasion

EMT-related cell-matrix interactions are linked to states of cell unjamming in cancer spheroid invasion

Summary: Epithelial-to-mesenchymal transitions (EMT) and unjamming transitions provide two distinct pathways for cancer cells to become invasive, but it is still unclear to what extent these pathways are connected. Here, we addressed this question by performing 3D spheroid invasion assays on epithel...

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Bibliographic Details
Main Authors: Anouk van der Net, Zaid Rahman, Ankur D. Bordoloi, Iain Muntz, Peter ten Dijke, Pouyan E. Boukany, Gijsje H. Koenderink
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Biophysics
Biomechanics
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422402649X
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