Palmitoylethanolamide causes dose-dependent changes in brain function and the lipidome

Palmitoylethanolamide causes dose-dependent changes in brain function and the lipidome

The present studies were undertaken to understand the effects of the commonly used nutraceutical PEA on brain function and lipid chemistry. These studies using MRI and broad-scale lipidomics are without precedent in animal or human research. During the MRI scanning session awake rats were given one...

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Bibliographic Details
Main Authors: Shreyas Balaji, Taylor J. Woodward, Emily Richter, Arnold Chang, Richard Otiz, Praveen P. Kulkarni, Kaashyap Balaji, Heather B. Bradshaw, Craig F. Ferris
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Neuroscience
Subjects:
cerebellum
functional connectivity
BOLD imaging
sensorimotor cortex
lipidomics
endocannabinoids
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1506352/full
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