Human papilloma virus infection drives unique metabolic and immune profiles in head and neck and cervical cancers: implications for targeted therapies and prognostic markers

Human papilloma virus infection drives unique metabolic and immune profiles in head and neck and cervical cancers: implications for targeted therapies and prognostic markers

Abstract Human papillomavirus (HPV) is a key driver of head and neck squamous cell carcinoma (HNSCC) and cervical squamous cell carcinoma (CESC). Yet, these cancers exhibit distinct molecular and clinical features influenced by HPV status. This study utilizes RNA sequencing data from The Cancer Geno...

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Bibliographic Details
Main Authors: Saira Hamid, Mohd Shahnawaz Khan, Meraj Alam Khan, Naoshad Muhammad, Mayank Singh, Ammira S. Al-Shabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Human papillomavirus (HPV)
Head and neck squamous cell carcinoma (HNSCC)
Cervical squamous cell carcinoma (CESC)
Gene expression
Metabolic activity
Biomarkers
Online Access:https://doi.org/10.1007/s12672-025-02384-8
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