The combination of CDX2 expression status and tumor-infiltrating lymphocyte density as a prognostic factor in adjuvant FOLFOX-treated patients with stage III colorectal cancers

The combination of CDX2 expression status and tumor-infiltrating lymphocyte density as a prognostic factor in adjuvant FOLFOX-treated patients with stage III colorectal cancers

Background Colorectal carcinomas (CRCs) with caudal-type homeobox 2 (CDX2) loss are recognized to pursue an aggressive behavior but tend to be accompanied by a high density of tumor-infiltrating lymphocytes (TILs). However, little is known about whether there is an interplay between CDX2 loss and TI...

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Bibliographic Details
Main Authors: Ji-Ae Lee, Hye Eun Park, Hye-Yeong Jin, Lingyan Jin, Seung Yeon Yoo, Nam-Yun Cho, Jeong Mo Bae, Jung Ho Kim, Gyeong Hoon Kang
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2025-01-01
Series:Journal of Pathology and Translational Medicine
Subjects:
cd8 antigens
cdx2 transcription factor
colorectal neoplasms
prognosis
lymphocytes, tumor-infiltrating
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2024-09-26.pdf
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http://www.jpatholtm.org/upload/pdf/jptm-2024-09-26.pdf

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