Benzodiazepines compromise the outcome of cancer immunotherapy

Benzodiazepines compromise the outcome of cancer immunotherapy

Acyl CoA binding protein (ACBP, which is encoded by diazepam binding inhibitor, DBI) acts on the gamma-amino butyric acid (GABA) receptor type A via a specific binding site that is shared by diazepam and other benzodiazepines. Both ACBP/DBI and benzodiazepines act as positive allosteric modulators,...

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Bibliographic Details
Main Authors: Léa Montégut, Lisa Derosa, Meriem Messaoudene, Hui Chen, Flavia Lambertucci, Bertrand Routy, Laurence Zitvogel, Isabelle Martins, Guido Kroemer
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
Benzodiazepines
comedications
Immunotherapy
neuroendocrine factors
non-small cell lung cancer
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2413719
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https://www.tandfonline.com/doi/10.1080/2162402X.2024.2413719

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