Dietary caloric input and tumor growth accelerate senescence and modulate liver and adipose tissue crosstalk

Dietary caloric input and tumor growth accelerate senescence and modulate liver and adipose tissue crosstalk

Abstract Metabolic alterations are related to tumorigenesis and other age-related diseases that are accelerated by “Westernized” diets. In fact, hypercaloric nutrition is associated with an increased incidence of cancers and faster aging. Conversely, lifespan-extending strategies, such as caloric re...

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Main Authors: José Xavier do Nascimento Júnior, Júlia da Conceição Gomes, Ricardo Imbroisi Filho, Helber de Maia Valença, Jéssica Ristow Branco, Amanda Bandeira Araújo, Amanda de Oliveira Esteves Moreira, Letícia Diniz Crepaldi, Larissa Pereira Paixão, Alan C. Ochioni, Thainá M. Demaria, João Gabriel Bernardo Leandro, Livia Marques Casanova, Mauro Sola-Penna, Patricia Zancan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07451-y
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