Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings
This study evaluates the antibacterial properties and physicochemical characteristics of –tantalum-copper (Ta-Cu) coatings deposited on titanium alloy substrates using high-power magnetron sputtering. Implant-associated infections, particularly those caused by bacterial adhesion and biofilm formatio...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Heliyon |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024171617 |
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| author | Bagdat Azamatov Alexey Dzhes Alexander Borisov Daniyar Kaliyev Bauyrzhan Maratuly Amangeldi Sagidugumar Myakinin Alexandr Amanzhol Turlybekuly Sergei Plotnikov |
| author_facet | Bagdat Azamatov Alexey Dzhes Alexander Borisov Daniyar Kaliyev Bauyrzhan Maratuly Amangeldi Sagidugumar Myakinin Alexandr Amanzhol Turlybekuly Sergei Plotnikov |
| author_sort | Bagdat Azamatov |
| collection | DOAJ |
| description | This study evaluates the antibacterial properties and physicochemical characteristics of –tantalum-copper (Ta-Cu) coatings deposited on titanium alloy substrates using high-power magnetron sputtering. Implant-associated infections, particularly those caused by bacterial adhesion and biofilm formation, pose significant challenges in the field of orthopedic and dental implants. To address these issues, Ta-Cu coatings with varying copper content (∼3.0 wt%, ∼10 wt%, ∼17 wt% for TaCu-1, TaCu-2, and TaCu-3, respectively) and different thermal treatment conditions (400 °C, 500 °C, 600 °C) were assessed for their antibacterial efficacy against Escherichia coli, Staphylococcus aureus, Salmonella enterica, and Pseudomonas aeruginosa. The study utilized both the diffusion into agar method and the time-kill test to evaluate antibacterial activity. Results indicate that the TaCu-2 sample, particularly when annealed at 600 °C, demonstrated the highest bactericidal activity, especially against E. coli and P. aeruginosa. The findings highlight the critical role of optimizing both copper content and annealing temperature in enhancing the antibacterial properties of Cu-Ta coatings, making them promising candidates for preventing implant-associated infections. |
| format | Article |
| id | doaj-art-47edad9e512547af8c5ac1a9552b4cd4 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-47edad9e512547af8c5ac1a9552b4cd42025-01-17T04:50:15ZengElsevierHeliyon2405-84402025-01-01111e41130Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatingsBagdat Azamatov0Alexey Dzhes1Alexander Borisov2Daniyar Kaliyev3Bauyrzhan Maratuly4Amangeldi Sagidugumar5Myakinin Alexandr6Amanzhol Turlybekuly7Sergei Plotnikov8D. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanD. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanD. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanD. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanD. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanD. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanInstitute of Materials Engineering LLP, Astana, 010000, KazakhstanInstitute of Materials Engineering LLP, Astana, 010000, Kazakhstan; National Laboratory Astana, Nazarbayev University, Astana, 010000, Kazakhstan; Corresponding author. Institute of Materials Engineering LLP, Astana, 010000, Kazakhstan.D. Serikbayev East Kazakhstan Technical University, Oskemen, 070000, KazakhstanThis study evaluates the antibacterial properties and physicochemical characteristics of –tantalum-copper (Ta-Cu) coatings deposited on titanium alloy substrates using high-power magnetron sputtering. Implant-associated infections, particularly those caused by bacterial adhesion and biofilm formation, pose significant challenges in the field of orthopedic and dental implants. To address these issues, Ta-Cu coatings with varying copper content (∼3.0 wt%, ∼10 wt%, ∼17 wt% for TaCu-1, TaCu-2, and TaCu-3, respectively) and different thermal treatment conditions (400 °C, 500 °C, 600 °C) were assessed for their antibacterial efficacy against Escherichia coli, Staphylococcus aureus, Salmonella enterica, and Pseudomonas aeruginosa. The study utilized both the diffusion into agar method and the time-kill test to evaluate antibacterial activity. Results indicate that the TaCu-2 sample, particularly when annealed at 600 °C, demonstrated the highest bactericidal activity, especially against E. coli and P. aeruginosa. The findings highlight the critical role of optimizing both copper content and annealing temperature in enhancing the antibacterial properties of Cu-Ta coatings, making them promising candidates for preventing implant-associated infections.http://www.sciencedirect.com/science/article/pii/S2405844024171617 |
| spellingShingle | Bagdat Azamatov Alexey Dzhes Alexander Borisov Daniyar Kaliyev Bauyrzhan Maratuly Amangeldi Sagidugumar Myakinin Alexandr Amanzhol Turlybekuly Sergei Plotnikov Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings Heliyon |
| title | Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings |
| title_full | Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings |
| title_fullStr | Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings |
| title_full_unstemmed | Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings |
| title_short | Antibacterial properties of copper-tantalum thin films: The impact of copper content and thermal treatment on implant coatings |
| title_sort | antibacterial properties of copper tantalum thin films the impact of copper content and thermal treatment on implant coatings |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024171617 |
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