Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows
Significant physiological changes in transition cows affect dry matter intake and immune function. Vitamin E is a vital fat-soluble vitamin for cells, influencing their signal transduction. However, limited research discusses the changes in vitamin E levels in bovine peripheral blood leukocytes (PBL...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://dx.doi.org/10.1080/1828051X.2024.2430363 |
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| author | Cheng-Yan Li Jue-Sze Ng Hsin-I Chiang Jacky Peng-Wen Chan Chien-Kai Wang |
| author_facet | Cheng-Yan Li Jue-Sze Ng Hsin-I Chiang Jacky Peng-Wen Chan Chien-Kai Wang |
| author_sort | Cheng-Yan Li |
| collection | DOAJ |
| description | Significant physiological changes in transition cows affect dry matter intake and immune function. Vitamin E is a vital fat-soluble vitamin for cells, influencing their signal transduction. However, limited research discusses the changes in vitamin E levels in bovine peripheral blood leukocytes (PBL) during the transition period. This study aimed to investigate changes in lipid metabolites and vitamin E levels in the blood and to observe their relation to vitamin E and inflammatory-related cytokines changes in PBL during the transition period. The non-esterified fatty acid levels peaked on the day of calving, while the β-hydroxybutyrate levels gradually rose after calving. Additionally, the circulating levels of cholesterol and vitamin E gradually increase after calving. However, the vitamin E to cholesterol ratio was lower postpartum. In PBL, vitamin E levels in peripheral blood mononuclear cells increased postpartum. Based on the Pearson correlation analysis, postpartum lipid metabolites were correlated with cytokine expression in PBL. However, none of the blood indicators were associated with PBL’s vitamin E content. Additionally, the vitamin E content of PBL showed a positive correlation with their cytokine expression. In summary, this study observed significant changes in both serum lipid metabolites and vitamin E, while the vitamin E content of PBL remained relatively stable. Moreover, the vitamin E content in PBL positively correlates with cytokine expression, suggesting that the vitamin E levels in PBL during the transition period may be involved in regulating cytokines. Therefore, the impact of PBL vitamin E levels on its function warrants further investigation. |
| format | Article |
| id | doaj-art-47db0e3ddba4449cbad0b0119a78b54b |
| institution | Kabale University |
| issn | 1594-4077 1828-051X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj-art-47db0e3ddba4449cbad0b0119a78b54b2025-01-02T11:34:22ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2024-12-012311784179610.1080/1828051X.2024.24303632430363Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cowsCheng-Yan Li0Jue-Sze Ng1Hsin-I Chiang2Jacky Peng-Wen Chan3Chien-Kai Wang4Department of Animal Science, National Chung Hsing UniversityDepartment of Animal Science, National Chung Hsing UniversityDepartment of Animal Science, National Chung Hsing UniversityDepartment of Veterinary Medicine, National Chung Hsing UniversityDepartment of Animal Science, National Chung Hsing UniversitySignificant physiological changes in transition cows affect dry matter intake and immune function. Vitamin E is a vital fat-soluble vitamin for cells, influencing their signal transduction. However, limited research discusses the changes in vitamin E levels in bovine peripheral blood leukocytes (PBL) during the transition period. This study aimed to investigate changes in lipid metabolites and vitamin E levels in the blood and to observe their relation to vitamin E and inflammatory-related cytokines changes in PBL during the transition period. The non-esterified fatty acid levels peaked on the day of calving, while the β-hydroxybutyrate levels gradually rose after calving. Additionally, the circulating levels of cholesterol and vitamin E gradually increase after calving. However, the vitamin E to cholesterol ratio was lower postpartum. In PBL, vitamin E levels in peripheral blood mononuclear cells increased postpartum. Based on the Pearson correlation analysis, postpartum lipid metabolites were correlated with cytokine expression in PBL. However, none of the blood indicators were associated with PBL’s vitamin E content. Additionally, the vitamin E content of PBL showed a positive correlation with their cytokine expression. In summary, this study observed significant changes in both serum lipid metabolites and vitamin E, while the vitamin E content of PBL remained relatively stable. Moreover, the vitamin E content in PBL positively correlates with cytokine expression, suggesting that the vitamin E levels in PBL during the transition period may be involved in regulating cytokines. Therefore, the impact of PBL vitamin E levels on its function warrants further investigation.http://dx.doi.org/10.1080/1828051X.2024.2430363transition periodvitamin eperipheral blood leukocytescytokine expression |
| spellingShingle | Cheng-Yan Li Jue-Sze Ng Hsin-I Chiang Jacky Peng-Wen Chan Chien-Kai Wang Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows Italian Journal of Animal Science transition period vitamin e peripheral blood leukocytes cytokine expression |
| title | Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows |
| title_full | Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows |
| title_fullStr | Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows |
| title_full_unstemmed | Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows |
| title_short | Correlation among blood vitamin E levels, hematological parameters, and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows |
| title_sort | correlation among blood vitamin e levels hematological parameters and cytokine expression of peripheral blood leukocytes during the transition period in dairy cows |
| topic | transition period vitamin e peripheral blood leukocytes cytokine expression |
| url | http://dx.doi.org/10.1080/1828051X.2024.2430363 |
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