Antiviral mechanisms of guanylate-binding protein 5: versatile inhibition of multiple viral glycoproteins

ABSTRACT Guanylate-binding proteins (GBPs) are interferon-inducible cellular factors known to inhibit a wide variety of pathogens. Humans encode seven GBPs that have functionally diversified to provide broad protection against a variety of bacteria, protozoa, and viruses. Here, we discuss recent dat...

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Bibliographic Details
Main Authors: Daniel Sauter, Frank Kirchhoff
Format: Article
Language:English
Published: American Society for Microbiology 2024-11-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02374-24
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