Antibodies against integrin αvβ6 have high diagnostic accuracy for ulcerative colitis

Antibodies against integrin αvβ6 have high diagnostic accuracy for ulcerative colitis

BackgroundAnti-integrin αvβ6 IgG autoantibodies showed good sensitivity and optimal specificity in ulcerative colitis (UC) compared to controls. We aim at confirming the diagnostic accuracy of anti-integrin αvβ6 autoantibodies in an Italian multicentric cohort.MethodsThis observational multicentric...

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Main Authors: Patrick Bez, Martina Scapolan, Davide Giuseppe Ribaldone, Gian Paolo Caviglia, Silvia Zago, Cristina Trucco, Simone Frara, Antonino Caruso, Marta Ascolani, Michele Campigotto, Stefano Benvenuti, Stefano Martelossi, Lara De Lucchi, Marta Favero, Francesco Cinetto, Elisabetta Faggin, Laura Ventura, Marcello Rattazzi, Tilde Manetta, Giulio Mengozzi, Antonio Antico, Carla Felice
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
ulcerative colitis
Crohn’s disease
integrin αvβ6
diagnosis
inflammatory bowel disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1641329/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1641329/full

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