ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE
This research investigates the biochemical profile, antioxidant properties, and antigenotoxic activity of red seaweed (Gracilaria sp.) extract on micronuclei formation in peripheral blood erythrocytes of tilapia (Oreochromis niloticus) exposed to a methomyl-based pesticide. Results revealed a diver...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Baghdad University
2024-12-01
|
| Series: | The Iraqi Journal of Agricultural science |
| Subjects: | |
| Online Access: | https://www.jcoagri.uobaghdad.edu.iq/index.php/intro/article/view/2087 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841559975857487872 |
|---|---|
| author | R.A. Islamy V. Hasan Sze-Wan Poong Y. Kilawati A.P. Basir A.S. Kamarudin |
| author_facet | R.A. Islamy V. Hasan Sze-Wan Poong Y. Kilawati A.P. Basir A.S. Kamarudin |
| author_sort | R.A. Islamy |
| collection | DOAJ |
| description |
This research investigates the biochemical profile, antioxidant properties, and antigenotoxic activity of red seaweed (Gracilaria sp.) extract on micronuclei formation in peripheral blood erythrocytes of tilapia (Oreochromis niloticus) exposed to a methomyl-based pesticide. Results revealed a diverse phytochemical profile in the red seaweed extract, with the presence of alkaloids, triterpenoids, steroids, tannins, coumarins, terpenoids, quinine, phytosteroids, flavonoids, and phlobtannins. GC-MS analysis identified compounds such as Heptadecane, Neophytadine, Hexadecanoic acid, Oleic acid, and Adipic acid in the sample. The antioxidant activity exhibited a concentration-dependent response, demonstrating increased strength with higher extract concentrations. Antigenotoxic analysis indicated a significant reduction in micronuclei frequency in peripheral erythrocytes of tilapia. In conclusion, the research underscores the potential of red seaweed extract as a valuable natural resource with antioxidant properties and a mitigating effect on genotoxicity induced by pesticide exposure in aquatic organisms.
|
| format | Article |
| id | doaj-art-47a17bf662db42698375cbaf2a7474c5 |
| institution | Kabale University |
| issn | 0075-0530 2410-0862 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Baghdad University |
| record_format | Article |
| series | The Iraqi Journal of Agricultural science |
| spelling | doaj-art-47a17bf662db42698375cbaf2a7474c52025-01-05T07:04:15ZengBaghdad UniversityThe Iraqi Journal of Agricultural science0075-05302410-08622024-12-0155610.36103/5n7ygp68ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDER.A. IslamyV. HasanSze-Wan PoongY. KilawatiA.P. BasirA.S. Kamarudin This research investigates the biochemical profile, antioxidant properties, and antigenotoxic activity of red seaweed (Gracilaria sp.) extract on micronuclei formation in peripheral blood erythrocytes of tilapia (Oreochromis niloticus) exposed to a methomyl-based pesticide. Results revealed a diverse phytochemical profile in the red seaweed extract, with the presence of alkaloids, triterpenoids, steroids, tannins, coumarins, terpenoids, quinine, phytosteroids, flavonoids, and phlobtannins. GC-MS analysis identified compounds such as Heptadecane, Neophytadine, Hexadecanoic acid, Oleic acid, and Adipic acid in the sample. The antioxidant activity exhibited a concentration-dependent response, demonstrating increased strength with higher extract concentrations. Antigenotoxic analysis indicated a significant reduction in micronuclei frequency in peripheral erythrocytes of tilapia. In conclusion, the research underscores the potential of red seaweed extract as a valuable natural resource with antioxidant properties and a mitigating effect on genotoxicity induced by pesticide exposure in aquatic organisms. https://www.jcoagri.uobaghdad.edu.iq/index.php/intro/article/view/2087antigenotoxicity, biochemical, gc-ms analysis, micronucleus, gracilaria. |
| spellingShingle | R.A. Islamy V. Hasan Sze-Wan Poong Y. Kilawati A.P. Basir A.S. Kamarudin ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE The Iraqi Journal of Agricultural science antigenotoxicity, biochemical, gc-ms analysis, micronucleus, gracilaria. |
| title | ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE |
| title_full | ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE |
| title_fullStr | ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE |
| title_full_unstemmed | ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE |
| title_short | ANTIGENOTOXIC ACTIVITY OF GRACILARIA SP. ON ERYTHROCYTES OF NILE TILAPIA EXPOSED BY METHOMYL-BASED PESTICIDE |
| title_sort | antigenotoxic activity of gracilaria sp on erythrocytes of nile tilapia exposed by methomyl based pesticide |
| topic | antigenotoxicity, biochemical, gc-ms analysis, micronucleus, gracilaria. |
| url | https://www.jcoagri.uobaghdad.edu.iq/index.php/intro/article/view/2087 |
| work_keys_str_mv | AT raislamy antigenotoxicactivityofgracilariasponerythrocytesofniletilapiaexposedbymethomylbasedpesticide AT vhasan antigenotoxicactivityofgracilariasponerythrocytesofniletilapiaexposedbymethomylbasedpesticide AT szewanpoong antigenotoxicactivityofgracilariasponerythrocytesofniletilapiaexposedbymethomylbasedpesticide AT ykilawati antigenotoxicactivityofgracilariasponerythrocytesofniletilapiaexposedbymethomylbasedpesticide AT apbasir antigenotoxicactivityofgracilariasponerythrocytesofniletilapiaexposedbymethomylbasedpesticide AT askamarudin antigenotoxicactivityofgracilariasponerythrocytesofniletilapiaexposedbymethomylbasedpesticide |