Predictive factors for clinical cure in the treatment of HBeAg(−) chronic hepatitis B or compensated cirrhosis: a prospective observational study

Predictive factors for clinical cure in the treatment of HBeAg(−) chronic hepatitis B or compensated cirrhosis: a prospective observational study

BackgroundSequential or combined treatment with nucleos(t)ide analogs (NAs) and pegylated interferon alpha-2b (Peg-IFN-α-2b) can improve the clinical cure rate. However, its clinical application is limited due to the adverse reactions associated with IFN.MethodsA multi-center prospective observation...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yan-Qing Lv, Ru-Hua Guo, Kun-Yu Liu, Jia-Jie Li, Hui-Fan Ji
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Medicine
Subjects:	chronic hepatitis B compensated cirrhosis Peg-IFN-α-2b clinical cure predictive factors
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1483744/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Exploring using HBsAg to predict interferon treatment course to achieve clinical cure in chronic hepatitis B patients: a clinical study
by: Fei Yan, et al.
Published: (2025-01-01)

Achieving chronic hepatitis B functional cure: Factors and potential mechanisms
by: Jiarui Zheng, et al.
Published: (2025-01-01)

Predictors of HBsAg seroclearance in HBeAg-negative chronic hepatitis B patients treated with nucleotide analogs plus polyethylene glycol interferon
by: Yan Peng, et al.
Published: (2025-01-01)

Determinants of outcomes in patients with hepatitis B virus-decompensated cirrhosis
by: Yi-Jie Huang, et al.
Published: (2025-01-01)

Effect of HBeAg/anti-HBe coexistence on HBeAg seroconversion in treatment-naïve chronic hepatitis B patients with peginterferon-α
by: Kaimin Song, et al.
Published: (2025-02-01)

Risk of Cirrhosis in Patients with Non-alcoholic Fatty Liver Disease and Previous Viral Hepatitis B
by: S. N. Batskikh, et al.
Published: (2020-09-01)

Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis
by: Lu Cao, et al.
Published: (2025-01-01)

The significance of antibody to hepatitis B surface antigen in infection and clearance of hepatitis B virus
by: Ling Ding, et al.
Published: (2025-12-01)

Global temporal trends and projections of hepatitis B-related cirrhosis among adolescents and young adults from 1990 to 2035: an analysis based on the global burden of disease study 2021
by: Quanwei He, et al.
Published: (2025-01-01)

Identification of multiple complications as independent risk factors associated with 1-, 3-, and 5-year mortality in hepatitis B-associated cirrhosis patients
by: Duo Shen, et al.
Published: (2025-02-01)

Resolved Hepatitis B: Achieved or Imaginary Wellbeing?
by: S. N. Batskikh
Published: (2021-04-01)

Non-Invasive Test for Assessment of Liver Fibrosis in Chronic Hepatitis B
by: Ye Ji Jun, et al.
Published: (2024-11-01)

Transcriptomic and metabolomic analyses reveal the spatial role of carnitine metabolism in the progression of hepatitis B virus cirrhosis to hepatocellular carcinoma
by: Pengxiang Gao, et al.
Published: (2024-12-01)

The role of multifocal visual evoked potential in detection of minimal hepatic encephalopathy in patients with compensated liver cirrhosis
by: Reem M. Sabry, et al.
Published: (2025-02-01)

Risk of progression and the cause of mortality at chronic viral mixed-hepatitis
by: K. I. Yesmembetov, et al.
Published: (2013-07-01)

Protracted HBsAg-aemia in a Patient with Acute Hepatitis B
by: K. R. Dudina, et al.
Published: (2018-11-01)

Treatment of chronic hepatitis B: options, monitoring, special cases and adverse effects
by: Mateusz Litwin Litwin, et al.
Published: (2025-01-01)

Antiviral therapy and regression of liver fibrosis at chronic hepatitis B
by: D. T. Abdurakhmanov
Published: (2010-02-01)

A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis
by: Ruidong Mo, et al.
Published: (2025-02-01)

Infection with hepatitis C virus as a cause of cirrhosis – case study
by: Lidia Sierpińska, et al.
Published: (2025-01-01)

A Cytokine That Is Involved in Immune Responses in Chronic Hepatitis B Virus Patients
by: Noor R. Abady, et al.
Published: (2024-01-01)

Markers of chronic hepatitis B at patients with HIV-infection and treatment approaches
by: S. I. Maksimov, et al.
Published: (2010-11-01)

CORRELATION BETWEEN SGOT AND SGPT LEVELS WITH POSITIVE HBsAg LEVELS
by: Nisa'ur Rosyidah, et al.
Published: (2024-07-01)

Hepatic encephalopathy and spontaneous bacterial peritonitis are associated with increased liver-related readmissions in cirrhosis
by: Shan Wang, et al.
Published: (2025-01-01)

Inflammatory lipid biomarkers and transplant-free mortality risk in hepatitis B-related cirrhosis and hepatic encephalopathy
by: Ke Shi, et al.
Published: (2025-01-01)

Quantitative dynamic evaluation HBsAg in blood in comparison to viral load level in patients with chronic HBV-monoinfection
by: K. R. Dudina, et al.
Published: (2011-06-01)

Factors associated with seropositivity of Hepatitis B & C: A case control study at Azad Jammu and Kashmir
by: Muhammad Abdul Quddus, et al.
Published: (2023-04-01)

Long-Term Results of the Etiotropic Therapy of Subcompensed Liver Cirrhosis in the Outcome of Chronic Hepatitis C
by: P. O. Bogomolov, et al.
Published: (2020-01-01)

Risk factors of development of hepatocellular carcinoma
by: V. T. Ivashkin, et al.
Published: (2009-02-01)

Timosin alpha-1 immunomodulating properties
by: M. V. Mayevskaya
Published: (2009-02-01)

单克隆多克隆抗体不同标记ELISA技术对HBeAg/抗-HBe检测评估
Published: (1993-01-01)

Wilson’s Disease and Autoimmune Hepatitis Coexistence: A Cause of Diagnostic Delay
by: Mohammed G Mudawi, et al.
Published: (2023-09-01)

Benefits of Liver Volume and Serum Zinc Level Assessment for the Screening of Covert Hepatic Encephalopathy in Patients with Child–Pugh Class A Cirrhosis
by: Masanori Fukushima, et al.
Published: (2024-12-01)

Implementation of a Hepatitis B Screening Program in Patients Receiving Systemic Anti-Cancer Therapy
by: Jennifer Leigh, et al.
Published: (2024-12-01)

High-Throughput Analysis of the T Cell Receptor Beta Chain Repertoire in PBMCs from Chronic Hepatitis B Patients with HBeAg Seroconversion
by: Yachao Qu, et al.
Published: (2016-01-01)

Comparison of the performances between ChatGPT and Gemini in answering questions on viral hepatitis
by: Meryem Sahin Ozdemir, et al.
Published: (2025-01-01)

Experience of entecavir in renal graft recipients with chronic hepatitis B
by: M. L. Zubkin, et al.
Published: (2011-09-01)

Role of the Aspartate Transaminase and Platelet Ratio Index in Assessing Hepatic Fibrosis and Liver Inflammation in Adolescent Patients with HBeAg-Positive Chronic Hepatitis B
by: Yu Zhijian, et al.
Published: (2015-01-01)

Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq
by: Salih A. Hama
Published: (2025-02-01)

Global progress, challenges and strategies in eliminating public threat of viral hepatitis
by: Sihui Zhang, et al.
Published: (2025-02-01)