Intrinsic PD‐L1 Degradation Induced by a Novel Self‐Assembling Hexapeptide for Enhanced Cancer Immunotherapy
Abstract Programmed death‐ligand 1 (PD‐L1) is a critical immune checkpoint protein that facilitates tumor immune evasion. While antibody‐based PD‐1/PD‐L1 inhibitors have shown promise, their limitations necessitate the development of alternative therapeutic strategies. This work addresses these chal...
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Main Authors: | Hongxia Zhang, Ming Ji, Yamei Wang, Mengmeng Jiang, Zongyu Lv, Gongyu Li, Lulu Wang, Zhen Zheng |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-01-01
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Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202410145 |
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