Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications
Oral squamous cell carcinoma (OSCC) accounts for approximately 90% of all oral cancers, significantly impacting the survival and quality of life of patients. Exosomes, small extracellular vesicles released by cells, play a crucial role in intercellular communication in cancer. Nevertheless, their fu...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1502283/full |
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| _version_ | 1841527018154360832 |
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| author | Bo Zhao Bo Zhao Zuntai Li Ronghua Li |
| author_facet | Bo Zhao Bo Zhao Zuntai Li Ronghua Li |
| author_sort | Bo Zhao |
| collection | DOAJ |
| description | Oral squamous cell carcinoma (OSCC) accounts for approximately 90% of all oral cancers, significantly impacting the survival and quality of life of patients. Exosomes, small extracellular vesicles released by cells, play a crucial role in intercellular communication in cancer. Nevertheless, their function and mechanism in OSCC remain elusive. Search Pubmed, Web of Science, and Cochrane Library using keywords OSCC, exome, diagnosis, and treatment to review the research progress of exome in OSCC. Based on these results, this review starting from the biosynthesis, structure, and contents of exosomes, elaborates on the research progress of exosomes in the diagnosis and treatment of OSCC. It explores the potential of exosomes in the diagnosis and treatment of OSCC, and briefly describes the challenges researchers currently face. |
| format | Article |
| id | doaj-art-478813f1a23c4a6aab8670c8f35ea0ce |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-478813f1a23c4a6aab8670c8f35ea0ce2025-01-16T06:10:33ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.15022831502283Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applicationsBo Zhao0Bo Zhao1Zuntai Li2Ronghua Li3Key Laboratory of Advanced Intelligent Protective Equipment Technology (Hebei University of Technology), Ministry of Education, Tianjin, ChinaDepartment of Stomatology, Tianjin First Central Hospital, Tianjin, ChinaDepartment of Stomatology, Tianjin First Central Hospital, Tianjin, ChinaDepartment of Stomatology, Tianjin First Central Hospital, Tianjin, ChinaOral squamous cell carcinoma (OSCC) accounts for approximately 90% of all oral cancers, significantly impacting the survival and quality of life of patients. Exosomes, small extracellular vesicles released by cells, play a crucial role in intercellular communication in cancer. Nevertheless, their function and mechanism in OSCC remain elusive. Search Pubmed, Web of Science, and Cochrane Library using keywords OSCC, exome, diagnosis, and treatment to review the research progress of exome in OSCC. Based on these results, this review starting from the biosynthesis, structure, and contents of exosomes, elaborates on the research progress of exosomes in the diagnosis and treatment of OSCC. It explores the potential of exosomes in the diagnosis and treatment of OSCC, and briefly describes the challenges researchers currently face.https://www.frontiersin.org/articles/10.3389/fonc.2024.1502283/fullextracellular vesiclesbiological characteristicsOSCConcologyexosomes |
| spellingShingle | Bo Zhao Bo Zhao Zuntai Li Ronghua Li Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications Frontiers in Oncology extracellular vesicles biological characteristics OSCC oncology exosomes |
| title | Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications |
| title_full | Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications |
| title_fullStr | Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications |
| title_full_unstemmed | Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications |
| title_short | Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications |
| title_sort | exosomes in oral squamous cell carcinoma functions challenges and potential applications |
| topic | extracellular vesicles biological characteristics OSCC oncology exosomes |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1502283/full |
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