Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies
AF is a prevalent condition that is associated with various modifiable and unmodifiable risk factors. Drug-induced AF, despite being commonly under-recognised, can be relatively easy to manage. Numerous cardiovascular and non-cardiovascular agents, including catecholaminergic agents, adenosine, anti...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2024-04-01
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| Series: | Arrhythmia & Electrophysiology Review |
| Online Access: | https://www.aerjournal.com/articleindex/aer.2023.24 |
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| _version_ | 1846122315083939840 |
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| author | Bingxun Li Mingjie Lin Lin Wu |
| author_facet | Bingxun Li Mingjie Lin Lin Wu |
| author_sort | Bingxun Li |
| collection | DOAJ |
| description | AF is a prevalent condition that is associated with various modifiable and unmodifiable risk factors. Drug-induced AF, despite being commonly under-recognised, can be relatively easy to manage. Numerous cardiovascular and non-cardiovascular agents, including catecholaminergic agents, adenosine, anti-tumour agents and others, have been reported to induce AF. However, the mechanisms underlying drug-induced AF are diverse and not fully understood. The complexity of clinical scenarios and insufficient knowledge regarding drug-induced AF have rendered the management of this condition complicated, and current treatment guidelines follow those for other types of AF. Here, we present a review of the epidemiology of drug-induced AF and highlight a range of drugs that can induce or exacerbate AF, along with their molecular and electrophysiological mechanisms. Given the inadequate evidence and lack of attention, further research is crucial to underscore the clinical significance of drug-induced AF, clarify the underlying mechanisms and develop effective treatment strategies for the condition. |
| format | Article |
| id | doaj-art-4724e67d9c9b4a9d888ad13cdde8f13a |
| institution | Kabale University |
| issn | 2050-3369 2050-3377 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Arrhythmia & Electrophysiology Review |
| spelling | doaj-art-4724e67d9c9b4a9d888ad13cdde8f13a2024-12-14T16:04:58ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33692050-33772024-04-011310.15420/aer.2023.24Drug-induced AF: Arrhythmogenic Mechanisms and Management StrategiesBingxun Li0Mingjie Lin1Lin Wu2Department of Cardiology, Peking University First Hospital, Beijing, ChinaDepartment of Cardiology, Qilu Hospital of Shandong University Qingdao Branch, Qingdao, ChinaDepartment of Cardiology, Peking University First Hospital, Beijing, China; Key Laboratory of Medical Electrophysiology of the Ministry of Education and Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, ChinaAF is a prevalent condition that is associated with various modifiable and unmodifiable risk factors. Drug-induced AF, despite being commonly under-recognised, can be relatively easy to manage. Numerous cardiovascular and non-cardiovascular agents, including catecholaminergic agents, adenosine, anti-tumour agents and others, have been reported to induce AF. However, the mechanisms underlying drug-induced AF are diverse and not fully understood. The complexity of clinical scenarios and insufficient knowledge regarding drug-induced AF have rendered the management of this condition complicated, and current treatment guidelines follow those for other types of AF. Here, we present a review of the epidemiology of drug-induced AF and highlight a range of drugs that can induce or exacerbate AF, along with their molecular and electrophysiological mechanisms. Given the inadequate evidence and lack of attention, further research is crucial to underscore the clinical significance of drug-induced AF, clarify the underlying mechanisms and develop effective treatment strategies for the condition.https://www.aerjournal.com/articleindex/aer.2023.24 |
| spellingShingle | Bingxun Li Mingjie Lin Lin Wu Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies Arrhythmia & Electrophysiology Review |
| title | Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies |
| title_full | Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies |
| title_fullStr | Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies |
| title_full_unstemmed | Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies |
| title_short | Drug-induced AF: Arrhythmogenic Mechanisms and Management Strategies |
| title_sort | drug induced af arrhythmogenic mechanisms and management strategies |
| url | https://www.aerjournal.com/articleindex/aer.2023.24 |
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