Neuronal subset-specific Pten-deficient mice do not exhibit deficits in sensorimotor gating processes [version 3; peer review: 1 approved, 2 approved with reservations]

Background: Deficits in sensorimotor gating have been reported in individuals with autism spectrum disorder (ASD), as well as in ASD murine models. However, this behavior has not been examined in the neuronal subset-specific (NS)-Pten knockout (KO) model of ASD. NS-Pten KO mice exhibit hyperactivity...

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Main Authors: Matthew S. Binder, Joaquin N. Lugo, Suzanne O. Nolan
Format: Article
Language:English
Published: F1000 Research Ltd 2020-04-01
Series:F1000Research
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Online Access:https://f1000research.com/articles/8-1727/v3
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