Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research
Depression is one of the most common diseases in the world, and it is also the most common mental disorder. Depressive disorders are a real threat not only to individuals, but also to the general population. This disease is a leading cause of disability and inability to work. Due to the numerous sid...
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MDPI AG
2024-11-01
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| Series: | Pharmaceuticals |
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| author | Renata Nurzyńska-Wierdak |
| author_facet | Renata Nurzyńska-Wierdak |
| author_sort | Renata Nurzyńska-Wierdak |
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| description | Depression is one of the most common diseases in the world, and it is also the most common mental disorder. Depressive disorders are a real threat not only to individuals, but also to the general population. This disease is a leading cause of disability and inability to work. Due to the numerous side effects of conventional drugs, attention is increasingly being paid to other solutions, including herbal medicines. Many plant species are known for their traditional uses in the treatment of anxiety, insomnia, and depression. The clinically proven effects of adaptogenic raw materials on depression symptoms are probably related to the positive impact of some secondary metabolites (terpenoids, alkaloids, glucosinolates, phenols). Currently, it is emphasized that in many cases the antioxidant and anti-inflammatory properties of plant substances play a protective role at the neurocellular level. Among the medicinal plants analyzed in clinical trials for the treatment of depression, the following seem to be particularly interesting: saffron (Crocus L.), turmeric (Curcuma L.), ginkgo (Ginkgo L.), St. John’s wort (Hypericum L.), and passionflower (Passiflora L.), which have broad and strong biological activity, well-documented history of action and use, and effectiveness in preventing and/or treating anxiety and depression. These plants are still in the sphere of biochemical and phytopharmaceutical research, the results of which are very promising. |
| format | Article |
| id | doaj-art-46be8ce7590b44a4aad43ff2bfd7f3ef |
| institution | Kabale University |
| issn | 1424-8247 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
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| series | Pharmaceuticals |
| spelling | doaj-art-46be8ce7590b44a4aad43ff2bfd7f3ef2024-11-26T18:17:22ZengMDPI AGPharmaceuticals1424-82472024-11-011711148910.3390/ph17111489Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and ResearchRenata Nurzyńska-Wierdak0Department of Vegetable and Herb Crops, Faculty of Horticulture and Landscape Architecture, University of Life Sciences in Lublin, Doświadczalna 50a, 20-280 Lublin, PolandDepression is one of the most common diseases in the world, and it is also the most common mental disorder. Depressive disorders are a real threat not only to individuals, but also to the general population. This disease is a leading cause of disability and inability to work. Due to the numerous side effects of conventional drugs, attention is increasingly being paid to other solutions, including herbal medicines. Many plant species are known for their traditional uses in the treatment of anxiety, insomnia, and depression. The clinically proven effects of adaptogenic raw materials on depression symptoms are probably related to the positive impact of some secondary metabolites (terpenoids, alkaloids, glucosinolates, phenols). Currently, it is emphasized that in many cases the antioxidant and anti-inflammatory properties of plant substances play a protective role at the neurocellular level. Among the medicinal plants analyzed in clinical trials for the treatment of depression, the following seem to be particularly interesting: saffron (Crocus L.), turmeric (Curcuma L.), ginkgo (Ginkgo L.), St. John’s wort (Hypericum L.), and passionflower (Passiflora L.), which have broad and strong biological activity, well-documented history of action and use, and effectiveness in preventing and/or treating anxiety and depression. These plants are still in the sphere of biochemical and phytopharmaceutical research, the results of which are very promising.https://www.mdpi.com/1424-8247/17/11/1489mental disordersherbal medicinesantidepressantsmechanisms of action |
| spellingShingle | Renata Nurzyńska-Wierdak Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research Pharmaceuticals mental disorders herbal medicines antidepressants mechanisms of action |
| title | Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research |
| title_full | Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research |
| title_fullStr | Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research |
| title_full_unstemmed | Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research |
| title_short | Plants with Potential Importance in Supporting the Treatment of Depression: Current Trends, and Research |
| title_sort | plants with potential importance in supporting the treatment of depression current trends and research |
| topic | mental disorders herbal medicines antidepressants mechanisms of action |
| url | https://www.mdpi.com/1424-8247/17/11/1489 |
| work_keys_str_mv | AT renatanurzynskawierdak plantswithpotentialimportanceinsupportingthetreatmentofdepressioncurrenttrendsandresearch |