Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress

Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress

ABSTRACT Homologous recombination (HR) is a universally conserved mechanism of DNA strand exchange between homologous sequences, driven in bacteria by the RecA recombinase. HR is key for the maintenance of bacterial genomes via replication fork restart and DNA repair, as well as for their plasticity...

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Bibliographic Details
Main Authors: David De Lemos, Anne-Lise Soulet, Violette Morales, Mathieu Berge, Patrice Polard, Calum Johnston
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:mBio
Subjects:
homologous recombination
transformation
genome maintenance
competence
tolerance
Online Access:https://journals.asm.org/doi/10.1128/mbio.03142-24
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