Pharmacogenomic insights into amlodipine response: the role of CACNA1D, CACNA1C, and TRIB3 variants in hypertensive patients.

Pharmacogenomic insights into amlodipine response: the role of CACNA1D, CACNA1C, and TRIB3 variants in hypertensive patients.

Hypertension affects over 1.28 billion individuals worldwide, yet response variability to calcium channel blockers (CCBs) like amlodipine remains a challenge. While pharmacogenomic studies have implicated genetic polymorphisms in treatment outcomes, the combined effects of multiple variants remain u...

Full description

Saved in:
Bibliographic Details
Main Authors: Wahby M Babaresh, Zakiullah, Sohaib Ahmad Sohail, Alija Baig, Malik Faisal, Aiman Begum, Haseenullah Shah, Zia Ul Hassan, Kiran Ijaz, Syed Muhammad Mukarram Shah, Aftab Ullah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329263
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1371/journal.pone.0329263

Similar Items