Development of sustained-release floating tablets of diltiazem hydrochloride

Development of sustained-release floating tablets of diltiazem hydrochloride

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Diltiazem hydrochloride (DTZ), utilised for cardiovascular conditions, possesses a short half-life, necessitating frequent dosing. To enhance compliance, sustainedrelease (SR) floating tablets were developed using a Quality by Design (QbD) approach. This study aimed to formulate DTZ 120 mg tablets,...

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Bibliographic Details
Main Authors: Hung Pham Van, Tung Nguyen Thanh, Nhat Hoang Thi Anh, Hieu Bui Trung, Uyen Dinh Thi Thu, Duyen Nguyen Thi Thanh
Format: Article
Language:English
Published: Vietnam Ministry of Science and Technology 2025-07-01
Series:Vietnam Journal of Science, Technology and Engineering
Subjects:
diltiazem hydrochloride
floating
quality by design
sustained-release
tablets
Online Access:https://www.vietnamscience.vjst.vn/index.php/vjste/article/view/1309
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