Formulation and evaluation of cetuximab functionalized phospholipid modified nanocrystals of paclitaxel for non-small cell lung cancer therapy

Formulation and evaluation of cetuximab functionalized phospholipid modified nanocrystals of paclitaxel for non-small cell lung cancer therapy

Abstract Present work aims to prepare Soluplus stabilized, phospholipid-modified, and cetuximab-conjugated paclitaxel nanocrystals (NCs) as stable nanocarriers for targeted drug delivery. The NCs, prepared using concurrent antisolvent precipitation cum cold crystallization method followed by probe s...

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Bibliographic Details
Main Authors: Manish Kumar, Pooja Goswami, Abhishek Jha, Manjit Manjit, Amol Parasram Satpute, Biplob Koch, Brahmeshwar Mishra
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Nanocrystals
Paclitaxel
Cetuximab
Lung cancer
Online Access:https://doi.org/10.1038/s41598-024-80283-8
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