Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

Abstract The cryo-electron microscopy (cryoEM) method has enabled high-resolution structure determination of numerous biomolecules and complexes. Nevertheless, cryoEM sample preparation of challenging proteins and complexes, especially those with low abundance or with preferential orientation, remai...

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Main Authors: Jianbing Ma, Gangshun Yi, Mingda Ye, Craig MacGregor-Chatwin, Yuewen Sheng, Ying Lu, Ming Li, Qingrong Li, Dong Wang, Robert J. C. Gilbert, Peijun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53745-w
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https://doi.org/10.1038/s41467-024-53745-w

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