Development of a Liposomal Dosage Form Based on Hydrophobic Derivative of Indolocarbazole

Development of a Liposomal Dosage Form Based on Hydrophobic Derivative of Indolocarbazole

Introduction. An original N-glycoside derivative of indolocarbazole LHS-1269 with a carbohydrate xylose residue was synthesized at the N.N. Blokhin Russian Cancer Research Center Ministry of Health of Russia. It is characterized by high antitumor activity against a number of transferable ascitic and...

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Bibliographic Details
Main Authors: B. Lugen, M. V. Dmitrieva, O. L. Orlova, I. I. Krasnyuk, I. I. Krasnyuk (jr.), D. O. Bokov, O. I. Stepanova, A. V. Belyackaya
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2020-08-01
Series:Разработка и регистрация лекарственных средств
Subjects:
indolocarbazole derivative
liposomes
egg phosphatidylcholine
dosage form
molar ratio
Online Access:https://www.pharmjournal.ru/jour/article/view/784
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