PostCOVID-19 Impact on Perinatal Outcomes
<b>Background.</b> Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) infection during pregnancy was associated with a number of adverse pregnancy outcomes, including miscarriage, preeclampsia, preterm birth, and stillbirth. The virus persistence can last for a long tim...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/15/1/57 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841549262810251264 |
|---|---|
| author | Gaukhar Kurmanova Ardak Ayazbekov Almagul Kurmanova Madina Rakhimbayeva Gulzhan Trimova Anarkul Kulembayeva |
| author_facet | Gaukhar Kurmanova Ardak Ayazbekov Almagul Kurmanova Madina Rakhimbayeva Gulzhan Trimova Anarkul Kulembayeva |
| author_sort | Gaukhar Kurmanova |
| collection | DOAJ |
| description | <b>Background.</b> Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) infection during pregnancy was associated with a number of adverse pregnancy outcomes, including miscarriage, preeclampsia, preterm birth, and stillbirth. The virus persistence can last for a long time, and the consequences of a previous coronavirus infection are currently under study. <b>Objectives.</b> This study aimed to establish the clinical features of the course of pregnancy and childbirth in women with a history of asymptomatic coronavirus disease 2019 (COVID-19). <b>Methods.</b> This study was conducted in the Regional Perinatal Center N3 of Turkestan city, Kazakhstan. A total of 229 participants were enrolled comprising individuals with (n = 133, exposed group) from August to September 2021 with a history of COVID-19 and without one in the same period in 2019 (n = 96, unexposed group). <b>Results.</b> There is a statistically significant strong association between a history of COVID-19 and the development of oligohydramnios (φ = 0.743, <i>p</i> < 0.001), and medium strength between a history of COVID-19 and the presence of anemia (φ = 0.254, <i>p</i> < 0.001), abnormal development of the placenta (φ = 0.254, <i>p</i> < 0.011), cord entanglement (φ = 0.343, <i>p</i> = 0.000), low birth weight (φ = 0.356, <i>p</i> < 0.001) and stillbirth (φ = 0.293, <i>p</i> < 0.001). <b>Conclusions.</b> The past COVID-19 infection in pregnant women has long-term consequences in the form of placenta abnormal development and oligohydramnios; and, as a result, the development of adverse perinatal outcomes |
| format | Article |
| id | doaj-art-458e4c0a0b6c4b2a99a5f5d9731eec62 |
| institution | Kabale University |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-458e4c0a0b6c4b2a99a5f5d9731eec622025-01-10T13:16:35ZengMDPI AGDiagnostics2075-44182024-12-011515710.3390/diagnostics15010057PostCOVID-19 Impact on Perinatal OutcomesGaukhar Kurmanova0Ardak Ayazbekov1Almagul Kurmanova2Madina Rakhimbayeva3Gulzhan Trimova4Anarkul Kulembayeva5Medicine and Healthcare Faculty, Al Farabi Kazakh National University, 71, Al-Farabi Avenue, 050040 Almaty, KazakhstanDepartment of Obstetrics and Gynecology, KA Yasawi International Kazakh-Turkish University, 161200 Turkistan, KazakhstanMedicine and Healthcare Faculty, Al Farabi Kazakh National University, 71, Al-Farabi Avenue, 050040 Almaty, KazakhstanMedicine and Healthcare Faculty, Al Farabi Kazakh National University, 71, Al-Farabi Avenue, 050040 Almaty, KazakhstanMedicine and Healthcare Faculty, Al Farabi Kazakh National University, 71, Al-Farabi Avenue, 050040 Almaty, KazakhstanCity Rheumatology Center, Masanchi Street, 92, 050022 Almaty, Kazakhstan<b>Background.</b> Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) infection during pregnancy was associated with a number of adverse pregnancy outcomes, including miscarriage, preeclampsia, preterm birth, and stillbirth. The virus persistence can last for a long time, and the consequences of a previous coronavirus infection are currently under study. <b>Objectives.</b> This study aimed to establish the clinical features of the course of pregnancy and childbirth in women with a history of asymptomatic coronavirus disease 2019 (COVID-19). <b>Methods.</b> This study was conducted in the Regional Perinatal Center N3 of Turkestan city, Kazakhstan. A total of 229 participants were enrolled comprising individuals with (n = 133, exposed group) from August to September 2021 with a history of COVID-19 and without one in the same period in 2019 (n = 96, unexposed group). <b>Results.</b> There is a statistically significant strong association between a history of COVID-19 and the development of oligohydramnios (φ = 0.743, <i>p</i> < 0.001), and medium strength between a history of COVID-19 and the presence of anemia (φ = 0.254, <i>p</i> < 0.001), abnormal development of the placenta (φ = 0.254, <i>p</i> < 0.011), cord entanglement (φ = 0.343, <i>p</i> = 0.000), low birth weight (φ = 0.356, <i>p</i> < 0.001) and stillbirth (φ = 0.293, <i>p</i> < 0.001). <b>Conclusions.</b> The past COVID-19 infection in pregnant women has long-term consequences in the form of placenta abnormal development and oligohydramnios; and, as a result, the development of adverse perinatal outcomeshttps://www.mdpi.com/2075-4418/15/1/57COVID-19pregnancyplacentastillbirtholigohydramnios |
| spellingShingle | Gaukhar Kurmanova Ardak Ayazbekov Almagul Kurmanova Madina Rakhimbayeva Gulzhan Trimova Anarkul Kulembayeva PostCOVID-19 Impact on Perinatal Outcomes Diagnostics COVID-19 pregnancy placenta stillbirth oligohydramnios |
| title | PostCOVID-19 Impact on Perinatal Outcomes |
| title_full | PostCOVID-19 Impact on Perinatal Outcomes |
| title_fullStr | PostCOVID-19 Impact on Perinatal Outcomes |
| title_full_unstemmed | PostCOVID-19 Impact on Perinatal Outcomes |
| title_short | PostCOVID-19 Impact on Perinatal Outcomes |
| title_sort | postcovid 19 impact on perinatal outcomes |
| topic | COVID-19 pregnancy placenta stillbirth oligohydramnios |
| url | https://www.mdpi.com/2075-4418/15/1/57 |
| work_keys_str_mv | AT gaukharkurmanova postcovid19impactonperinataloutcomes AT ardakayazbekov postcovid19impactonperinataloutcomes AT almagulkurmanova postcovid19impactonperinataloutcomes AT madinarakhimbayeva postcovid19impactonperinataloutcomes AT gulzhantrimova postcovid19impactonperinataloutcomes AT anarkulkulembayeva postcovid19impactonperinataloutcomes |