Broad-spectrum inflammasome inhibition by thiomuscimol

Abstract Inflammasome formation, arising from pathogen or internal activating signals, is a key step in canonical pyroptosis, a gasdermin-mediated inflammatory cell death. Inhibition of pyroptosis has great clinical relevance due to its involvement in many different disease states. Current inhibitor...

Full description

Saved in:
Bibliographic Details
Main Authors: Marisa J. Anderson, Andreas B. den Hartigh, Wendy P. Loomis, Susan L. Fink
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02238-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items