Broad-spectrum inflammasome inhibition by thiomuscimol
Abstract Inflammasome formation, arising from pathogen or internal activating signals, is a key step in canonical pyroptosis, a gasdermin-mediated inflammatory cell death. Inhibition of pyroptosis has great clinical relevance due to its involvement in many different disease states. Current inhibitor...
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| Main Authors: | Marisa J. Anderson, Andreas B. den Hartigh, Wendy P. Loomis, Susan L. Fink |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-11-01
|
| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-024-02238-2 |
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