Author response to Colle et al

The event of pseudoprogression is rare in patients with MSI-high metastatic colorectal cancer receiving immune checkpoint inhibitors. In this response to the Letter to the Editor by Colle et al, we highlight that the timing of disease re-assessment may influence the incidence of pseudoprogression, w...

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Main Authors: Giovanni Fucà, Filippo Pietrantonio, Francesca Corti
Format: Article
Language:English
Published: BMJ Publishing Group 2021-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/6/e003138.full
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author Giovanni Fucà
Filippo Pietrantonio
Francesca Corti
author_facet Giovanni Fucà
Filippo Pietrantonio
Francesca Corti
author_sort Giovanni Fucà
collection DOAJ
description The event of pseudoprogression is rare in patients with MSI-high metastatic colorectal cancer receiving immune checkpoint inhibitors. In this response to the Letter to the Editor by Colle et al, we highlight that the timing of disease re-assessment may influence the incidence of pseudoprogression, with early assessments being associated with higher incidence. Such dynamics should be considered when interpreting the efficacy of treatment.
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institution Kabale University
issn 2051-1426
language English
publishDate 2021-06-01
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series Journal for ImmunoTherapy of Cancer
spelling doaj-art-4541f8066c2d4353b4de9fdeee044e9e2024-11-08T20:35:07ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262021-06-019610.1136/jitc-2021-003138Author response to Colle et alGiovanni Fucà0Filippo Pietrantonio1Francesca Corti21 Department of Gynecologic Oncology, Humanitas San Pio X, Milan, ItalyMedical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, ItalyDepartment of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, ItalyThe event of pseudoprogression is rare in patients with MSI-high metastatic colorectal cancer receiving immune checkpoint inhibitors. In this response to the Letter to the Editor by Colle et al, we highlight that the timing of disease re-assessment may influence the incidence of pseudoprogression, with early assessments being associated with higher incidence. Such dynamics should be considered when interpreting the efficacy of treatment.https://jitc.bmj.com/content/9/6/e003138.full
spellingShingle Giovanni Fucà
Filippo Pietrantonio
Francesca Corti
Author response to Colle et al
Journal for ImmunoTherapy of Cancer
title Author response to Colle et al
title_full Author response to Colle et al
title_fullStr Author response to Colle et al
title_full_unstemmed Author response to Colle et al
title_short Author response to Colle et al
title_sort author response to colle et al
url https://jitc.bmj.com/content/9/6/e003138.full
work_keys_str_mv AT giovannifuca authorresponsetocolleetal
AT filippopietrantonio authorresponsetocolleetal
AT francescacorti authorresponsetocolleetal