Neutrophils enhance the clearance of systemic amyloid deposits in a murine amyloidoma model

Neutrophils enhance the clearance of systemic amyloid deposits in a murine amyloidoma model

IntroductionAmyloid-specific antibodies have been shown to opsonize and enhance amyloid clearance in systemic amyloidosis mouse models. However, the immunological mechanisms by which amyloid is removed have not been clearly defined. Previous reports from preclinical in vivo studies suggest polymorph...

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Bibliographic Details
Main Authors: Trevor J. Hancock, Marina Vlasyuk, James S. Foster, Sallie Macy, Daniel C. Wooliver, Manasi Balachandran, Angela D. Williams, Emily B. Martin, Stephen J. Kennel, Eric R. Heidel, Jonathan S. Wall, Joseph W. Jackson
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
AL amyloidosis
neutrophils in amyloid
neutrophil NETs
amyloid phagocytosis
amyloid resolution
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1487250/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1487250/full

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