Efficacy of ceftazidime-avibactam with or without polymyxin for carbapenem-resistant Klebsiella pneumoniae infections after initial treatment with polymyxin

Efficacy of ceftazidime-avibactam with or without polymyxin for carbapenem-resistant Klebsiella pneumoniae infections after initial treatment with polymyxin

ABSTRACT Although polymyxins are a suboptimal option for difficult-to-treat resistant infections, they are still preferred as the first-line treatment, especially in low- and middle-income countries. This study assesses the efficacy of ceftazidime-avibactam (CAZ-AVI) following polymyxin B failure in...

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Bibliographic Details
Main Authors: Jingli Lu, Yani Ma, Zhe Cao, Baoling Zhu, Luna Fan, Haiyang Meng
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
ceftazidime-avibactam
polymyxin B
carbapenem-resistant Enterobacteriaceae
salvage therapy
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01770-24
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