Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway

Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway

Abstract Studies have confirmed that elevated glucose levels could lead to renal fibrosis through the process of ferroptosis. Liraglutide, a human glucagon-like peptide-1 (GLP-1) analogue, is a potential treatment option for diabetes. This study aimed to examine the potential of liraglutide (LIRA) i...

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Bibliographic Details
Main Authors: Qi Chen, Ji-Xian Song, Zhi Zhang, Ji-Ren An, Yu-Jing Gou, Miao Tan, Yashuo Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
High glucose
Lipid peroxidation
Iron overload
Fsp1-CoQ10-NAD(P)H pathway
Online Access:https://doi.org/10.1038/s41598-025-85658-z
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