Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review
Pyridine derivatives have emerged as promising candidates in the field of biomedical research, showcasing a wide array of applications in drug development and therapeutic interventions. The recent advances in the design and utilization of pyridine derivatives, focusing on their diverse roles in biom...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | European Journal of Medicinal Chemistry Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417424000827 |
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| author | Duryodhan Sahu P.S. Rama Sreekanth Prasanta Kumar Behera Manoj Kumar Pradhan Amit Patnaik Sachin Salunkhe Robert Cep |
| author_facet | Duryodhan Sahu P.S. Rama Sreekanth Prasanta Kumar Behera Manoj Kumar Pradhan Amit Patnaik Sachin Salunkhe Robert Cep |
| author_sort | Duryodhan Sahu |
| collection | DOAJ |
| description | Pyridine derivatives have emerged as promising candidates in the field of biomedical research, showcasing a wide array of applications in drug development and therapeutic interventions. The recent advances in the design and utilization of pyridine derivatives, focusing on their diverse roles in biomedical applications is the key understanding in this study. The versatility of pyridine-based compounds has been leveraged to address various challenges in the realms of pharmaceuticals and medicinal chemistry, offering innovative solutions for improved healthcare outcomes. This review encompasses the synthesis methodologies of pyridine derivatives, elucidating key synthetic strategies that enable the tailoring of these compounds for specific biomedical purposes and medicinal properties. This underscores the recent advancements in understanding the pharmacokinetics and pharmacodynamics of pyridine derivatives, emphasizing their potential impact on the future landscape of biomedical research. The synthesis and application of these compounds represent a dynamic frontier in drug development, offering innovative solutions to address unmet medical needs and propel the field toward more effective and personalized therapies. Pyridine derivatives play an important role in bio-imaging applications for the diagnosis of various diseases. Pyridine-based macromolecules have great potential for the efficient and specific delivery of drugs. |
| format | Article |
| id | doaj-art-445464c19acc4d2c91b9da8d614e3d0c |
| institution | Kabale University |
| issn | 2772-4174 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | European Journal of Medicinal Chemistry Reports |
| spelling | doaj-art-445464c19acc4d2c91b9da8d614e3d0c2024-12-05T05:21:54ZengElsevierEuropean Journal of Medicinal Chemistry Reports2772-41742024-12-0112100210Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive reviewDuryodhan Sahu0P.S. Rama Sreekanth1Prasanta Kumar Behera2Manoj Kumar Pradhan3Amit Patnaik4Sachin Salunkhe5Robert Cep6Department of Chemistry, NIST University, Institute Park, Pallur Hills, Berhampur, India; Corresponding author.School of Mechanical Engineering, VIT-AP University, Inavolu, Andhra Pradesh, 522237, India; Corresponding author.Department of Chemistry, NIST University, Institute Park, Pallur Hills, Berhampur, IndiaDepartment of Chemistry, NIST University, Institute Park, Pallur Hills, Berhampur, IndiaDepartment of Biotechnology, NIST University, Institute Park, Pallur Hills, Berhampur, IndiaDepartment of Mechanical Engineering, Gazi University Faculty of Engineering, Maltepe, ANKARA, 06570, Turkey; Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, IndiaDepartment of Machining, Assembly and Engineering Metrology, Faculty of Mechanical Engineering, VSB—Technical University of Ostrava, 70800, Ostrava, Czech RepublicPyridine derivatives have emerged as promising candidates in the field of biomedical research, showcasing a wide array of applications in drug development and therapeutic interventions. The recent advances in the design and utilization of pyridine derivatives, focusing on their diverse roles in biomedical applications is the key understanding in this study. The versatility of pyridine-based compounds has been leveraged to address various challenges in the realms of pharmaceuticals and medicinal chemistry, offering innovative solutions for improved healthcare outcomes. This review encompasses the synthesis methodologies of pyridine derivatives, elucidating key synthetic strategies that enable the tailoring of these compounds for specific biomedical purposes and medicinal properties. This underscores the recent advancements in understanding the pharmacokinetics and pharmacodynamics of pyridine derivatives, emphasizing their potential impact on the future landscape of biomedical research. The synthesis and application of these compounds represent a dynamic frontier in drug development, offering innovative solutions to address unmet medical needs and propel the field toward more effective and personalized therapies. Pyridine derivatives play an important role in bio-imaging applications for the diagnosis of various diseases. Pyridine-based macromolecules have great potential for the efficient and specific delivery of drugs.http://www.sciencedirect.com/science/article/pii/S2772417424000827Organic synthesisBiomedical researchPharmacokineticsMedicinal chemistryPyridine derivatives |
| spellingShingle | Duryodhan Sahu P.S. Rama Sreekanth Prasanta Kumar Behera Manoj Kumar Pradhan Amit Patnaik Sachin Salunkhe Robert Cep Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review European Journal of Medicinal Chemistry Reports Organic synthesis Biomedical research Pharmacokinetics Medicinal chemistry Pyridine derivatives |
| title | Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review |
| title_full | Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review |
| title_fullStr | Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review |
| title_full_unstemmed | Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review |
| title_short | Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review |
| title_sort | advances in synthesis medicinal properties and biomedical applications of pyridine derivatives a comprehensive review |
| topic | Organic synthesis Biomedical research Pharmacokinetics Medicinal chemistry Pyridine derivatives |
| url | http://www.sciencedirect.com/science/article/pii/S2772417424000827 |
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