The effect of fibroblast growth factor 2 on neovascular vessels depends on the stage of angiogenesis

The effect of fibroblast growth factor 2 on neovascular vessels depends on the stage of angiogenesis

Objective: The exact relationship between fibroblast growth factor 2 (FGF2) and choroidal neovascularization (CNV) remains unclear. In this study, using optical coherence tomography angiography (OCTA) and FGF2-tg mice which are transgenic mice with a rhodopsin promoter/FGF2 gene fusion, we aimed to...

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Main Authors: Yuki Hattori, Haruhiko Yamada, Hidetsugu Mori, Shinpei Oba, Kaito Yokota, Masatoshi Omi, Yuichi Yamamoto, Keiko Toyama, Masayuki Ohnaka, Kanji Takahashi, Hisanori Imai
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
FGF2
Vessels maturation
OCTA
Apelin
Ang1
PDGFRβ
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024158744
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