Effects of Probucol on plasma amyloid-β transport in patients with hyperlipidemia: a 12-week randomized, double-blind, placebo-controlled trial

Abstract Background Although dyslipidemia has been acknowledged as a risk factor for Alzheimer’s disease (AD), the effects of lipid-lowering drugs on AD have not been determined. The primary pathophysiological hallmark of AD is the deposition of amyloid-β (Aβ) plaques in the brain. Plasma Aβ levels...

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Main Authors: Liangjun Dang, Shan Wei, Yi Zhao, Rong Zhou, Suhang Shang, Fan Gao, Jingyi Wang, Jin Wang, Qiumin Qu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Lipids in Health and Disease
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Online Access:https://doi.org/10.1186/s12944-024-02398-1
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