Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications
The management and treatment of tumor complications pose continuous challenges due to the inherent complexity. However, the advent of drug delivery systems (DDSs) brings promising opportunities to address the tumor complications using innovative technological approaches. This review focuses on commo...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Materials Today Bio |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006424004368 |
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| author | Kerui Li Bei Guo Junmou Gu Na Ta Jia Gu Hao Yu Mengchi Sun Tao Han |
| author_facet | Kerui Li Bei Guo Junmou Gu Na Ta Jia Gu Hao Yu Mengchi Sun Tao Han |
| author_sort | Kerui Li |
| collection | DOAJ |
| description | The management and treatment of tumor complications pose continuous challenges due to the inherent complexity. However, the advent of drug delivery systems (DDSs) brings promising opportunities to address the tumor complications using innovative technological approaches. This review focuses on common oncological complications, including cancer thrombosis, malignant serous effusion, tumor-associated infections, cancer pain, and treatment-related complications. Emphasis was placed on the application and potential of DDSs in mitigating and treating these tumor complications, and we delved into the underlying mechanisms of common cancer-associated complications, discussed the limitations of conventional treatments, and outlined the current status and potential development of DDSs for various complications in this review. Moreover, we have discussed the existing challenges in DDSs research, underscoring the need for addressing issues related to biocompatibility and targeting of DDSs, optimizing drug delivery routes, and enhancing delivery efficiency and precision. In conclusion, DDSs offer promising avenues for treating cancer complications, offering the potential for the development of more effective and safer drug delivery strategies, thereby improving the quality of life and survival rates of cancer patients. |
| format | Article |
| id | doaj-art-4424f53955b2470b8e31cd73895377b3 |
| institution | Kabale University |
| issn | 2590-0064 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj-art-4424f53955b2470b8e31cd73895377b32025-01-17T04:52:00ZengElsevierMaterials Today Bio2590-00642025-02-0130101375Emerging advances in drug delivery systems (DDSs) for optimizing cancer complicationsKerui Li0Bei Guo1Junmou Gu2Na Ta3Jia Gu4Hao Yu5Mengchi Sun6Tao Han7Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, ChinaDepartment of Endocrinology, General Hospital of Northern Theater Command, Shenyang, 110001, ChinaDepartment of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, ChinaDepartment of Neurology, Second Affiliated Hospital of Dalian Medical University, Dalian, 116044, ChinaDepartment of Otolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China; Corresponding author. Department of Otolaryngology, The First Affiliated Hospital of China Medical University, No.155 Nanjing North Street, Heping District, Shenyang, Liaoning, 110001, China.Department of Endocrinology, General Hospital of Northern Theater Command, Shenyang, 110001, China; Corresponding author. Department of Endocrinology, General Hospital of Northern Theater Command, Shenyang, No.83 Wenhua Road, Shenyang, Liaoning, 110001, China.School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, China; Corresponding author. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, 110001, China; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, China; Corresponding authors. Department of Medical Oncology, the First Hospital of China Medical University, No.155 Nanjingbei Road, Shenyang, Liaoning 110001, PR China. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, China.The management and treatment of tumor complications pose continuous challenges due to the inherent complexity. However, the advent of drug delivery systems (DDSs) brings promising opportunities to address the tumor complications using innovative technological approaches. This review focuses on common oncological complications, including cancer thrombosis, malignant serous effusion, tumor-associated infections, cancer pain, and treatment-related complications. Emphasis was placed on the application and potential of DDSs in mitigating and treating these tumor complications, and we delved into the underlying mechanisms of common cancer-associated complications, discussed the limitations of conventional treatments, and outlined the current status and potential development of DDSs for various complications in this review. Moreover, we have discussed the existing challenges in DDSs research, underscoring the need for addressing issues related to biocompatibility and targeting of DDSs, optimizing drug delivery routes, and enhancing delivery efficiency and precision. In conclusion, DDSs offer promising avenues for treating cancer complications, offering the potential for the development of more effective and safer drug delivery strategies, thereby improving the quality of life and survival rates of cancer patients.http://www.sciencedirect.com/science/article/pii/S2590006424004368Drug delivery systems (DDSs)Tumor complicationsInherent complexityQuality of lifeSurvival rates |
| spellingShingle | Kerui Li Bei Guo Junmou Gu Na Ta Jia Gu Hao Yu Mengchi Sun Tao Han Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications Materials Today Bio Drug delivery systems (DDSs) Tumor complications Inherent complexity Quality of life Survival rates |
| title | Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications |
| title_full | Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications |
| title_fullStr | Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications |
| title_full_unstemmed | Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications |
| title_short | Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications |
| title_sort | emerging advances in drug delivery systems ddss for optimizing cancer complications |
| topic | Drug delivery systems (DDSs) Tumor complications Inherent complexity Quality of life Survival rates |
| url | http://www.sciencedirect.com/science/article/pii/S2590006424004368 |
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