Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male

Sertoli cell tumors are a rare type of sex-cord stromal tumor. We present a case of a thirteen-year-old male presenting with 2–3 months of fevers and twenty-pound weight loss. Evaluation revealed leukocytosis, anemia, elevated systemic inflammatory markers and a negative infectious disease evaluatio...

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Main Authors: Austin G. Kazarian, Caleb Q. Ashbrook, Charles F. Timmons, Craig A. Peters, Bruce J. Schlomer
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Urology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214442024002389
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author Austin G. Kazarian
Caleb Q. Ashbrook
Charles F. Timmons
Craig A. Peters
Bruce J. Schlomer
author_facet Austin G. Kazarian
Caleb Q. Ashbrook
Charles F. Timmons
Craig A. Peters
Bruce J. Schlomer
author_sort Austin G. Kazarian
collection DOAJ
description Sertoli cell tumors are a rare type of sex-cord stromal tumor. We present a case of a thirteen-year-old male presenting with 2–3 months of fevers and twenty-pound weight loss. Evaluation revealed leukocytosis, anemia, elevated systemic inflammatory markers and a negative infectious disease evaluation. An evaluation for malignancy revealed an incidental testicular mass. A radical orchiectomy lead to prompt resolution of fevers, leukocytosis, and elevated systemic inflammatory markers. Final pathology was consistent with a Sertoli cell tumor. To our knowledge, this is the first reported case of a Sertoli cell tumor presenting with fever, leukocytosis, and weight loss.
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publisher Elsevier
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series Urology Case Reports
spelling doaj-art-440117e36b6c495aa22826e3071a9dd12025-01-14T04:12:15ZengElsevierUrology Case Reports2214-44202025-01-0158102884Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old maleAustin G. Kazarian0Caleb Q. Ashbrook1Charles F. Timmons2Craig A. Peters3Bruce J. Schlomer4Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA; Corresponding author. Department of Urology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USADepartment of Pathology, UT Southwestern and Children's Medical Center, Dallas, TX, USADepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA; Division of Pediatric Urology, Children's Medical Center, Dallas, TX, USADepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA; Division of Pediatric Urology, Children's Medical Center, Dallas, TX, USASertoli cell tumors are a rare type of sex-cord stromal tumor. We present a case of a thirteen-year-old male presenting with 2–3 months of fevers and twenty-pound weight loss. Evaluation revealed leukocytosis, anemia, elevated systemic inflammatory markers and a negative infectious disease evaluation. An evaluation for malignancy revealed an incidental testicular mass. A radical orchiectomy lead to prompt resolution of fevers, leukocytosis, and elevated systemic inflammatory markers. Final pathology was consistent with a Sertoli cell tumor. To our knowledge, this is the first reported case of a Sertoli cell tumor presenting with fever, leukocytosis, and weight loss.http://www.sciencedirect.com/science/article/pii/S2214442024002389Testicular neoplasmsSertoli cell tumorParaneoplastic syndromePediatric oncology
spellingShingle Austin G. Kazarian
Caleb Q. Ashbrook
Charles F. Timmons
Craig A. Peters
Bruce J. Schlomer
Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male
Urology Case Reports
Testicular neoplasms
Sertoli cell tumor
Paraneoplastic syndrome
Pediatric oncology
title Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male
title_full Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male
title_fullStr Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male
title_full_unstemmed Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male
title_short Case report of a Sertoli cell tumor with unique presentation including fevers, weight loss, and leukocytosis in a 13-year-old male
title_sort case report of a sertoli cell tumor with unique presentation including fevers weight loss and leukocytosis in a 13 year old male
topic Testicular neoplasms
Sertoli cell tumor
Paraneoplastic syndrome
Pediatric oncology
url http://www.sciencedirect.com/science/article/pii/S2214442024002389
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