Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II (CaMKII) Regulates Basal Cardiac Pacemaker Function: Pros and Cons
The spontaneous firing of the sinoatrial (SA) node, the physiological pacemaker of the heart, is generated within sinoatrial nodal cells (SANCs) and is regulated by a “coupled-clock” pacemaker system, which integrates a “membrane clock”, the ensemble of ion channel currents, and an intracellular “Ca...
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Main Authors: | Tatiana M. Vinogradova, Edward G. Lakatta |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/14/1/3 |
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