Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer

The author analyzes an algorithm for identifying and treating w omen with cervical intraepithelial neoplasias (CIN) and microinv asive cancer of the cervix uteri in cases of the hidden area of transformation and in the absence of visible cervical changes. There are excep- tional difficulties of maki...

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Main Author: L. I. Korolenkova
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/181
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author L. I. Korolenkova
author_facet L. I. Korolenkova
author_sort L. I. Korolenkova
collection DOAJ
description The author analyzes an algorithm for identifying and treating w omen with cervical intraepithelial neoplasias (CIN) and microinv asive cancer of the cervix uteri in cases of the hidden area of transformation and in the absence of visible cervical changes. There are excep- tional difficulties of making the diagnosis of epithelial damages due to the incomplete reproducibility of cytological abnormal ities and the low informative value of a histological study of scrapes from the cervical canal. To avoid hypodiagnosis, it is justifiable to prefer human papillomavirus testing (Hybrid Capture 2 (HC2)) to repeat smears for the choice of a management tactic. Conization is recommend ed as a diagnostic and/or therapeutic procedure when the viral load is high in over 35-year-old patients with abnormal smears anda hidden transformation area.
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institution Kabale University
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1999-8627
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publishDate 2014-08-01
publisher ABV-press
record_format Article
series Опухоли женской репродуктивной системы
spelling doaj-art-43c1be0a5eb84c018f7d1ca6fa98f7582025-08-20T04:00:01ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-08-0103747810.17650/1994-4098-2011-0-3-74-78197Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancerL. I. Korolenkova0N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowThe author analyzes an algorithm for identifying and treating w omen with cervical intraepithelial neoplasias (CIN) and microinv asive cancer of the cervix uteri in cases of the hidden area of transformation and in the absence of visible cervical changes. There are excep- tional difficulties of making the diagnosis of epithelial damages due to the incomplete reproducibility of cytological abnormal ities and the low informative value of a histological study of scrapes from the cervical canal. To avoid hypodiagnosis, it is justifiable to prefer human papillomavirus testing (Hybrid Capture 2 (HC2)) to repeat smears for the choice of a management tactic. Conization is recommend ed as a diagnostic and/or therapeutic procedure when the viral load is high in over 35-year-old patients with abnormal smears anda hidden transformation area.https://ojrs.abvpress.ru/ojrs/article/view/181cervical intraepithelial neoplasiamicroinvasive cancersmear cytological abnormalitiesscreeninghybrid capture 2hypodiagnosis
spellingShingle L. I. Korolenkova
Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
Опухоли женской репродуктивной системы
cervical intraepithelial neoplasia
microinvasive cancer
smear cytological abnormalities
screening
hybrid capture 2
hypodiagnosis
title Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_full Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_fullStr Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_full_unstemmed Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_short Abnormal cervical smears in the unchanged uterine cervix: difficulties in the screening, diagnosis, and treatment of cervical intraepithelial neoplasias and microinvasive cancer
title_sort abnormal cervical smears in the unchanged uterine cervix difficulties in the screening diagnosis and treatment of cervical intraepithelial neoplasias and microinvasive cancer
topic cervical intraepithelial neoplasia
microinvasive cancer
smear cytological abnormalities
screening
hybrid capture 2
hypodiagnosis
url https://ojrs.abvpress.ru/ojrs/article/view/181
work_keys_str_mv AT likorolenkova abnormalcervicalsmearsintheunchangeduterinecervixdifficultiesinthescreeningdiagnosisandtreatmentofcervicalintraepithelialneoplasiasandmicroinvasivecancer