CXCL11 reprograms M2-biased macrophage polarization to alleviate pulmonary fibrosis in mice

CXCL11 reprograms M2-biased macrophage polarization to alleviate pulmonary fibrosis in mice

Abstract Background In understanding the pathophysiology of pulmonary fibrosis (PF), macrophage plasticity has been implicated with a crucial role in the fibrogenic process. Growing evidence indicates that accumulation of M2 macrophages correlates with the progression of PF, suggesting that targeted...

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Main Authors: Ji-Young Kim, Dong-Wook Cho, Jung-Yun Choi, Suji Jeong, Minje Kang, Woo Jin Kim, In-Sun Hong, Haengseok Song, Heesoon Chang, Se-Ran Yang, Seung-Joon Lee, Mira Park, Seok-Ho Hong
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell & Bioscience
Subjects:
Pulmonary fibrosis
Macrophage
Polarization
CXCL11
Online Access:https://doi.org/10.1186/s13578-024-01320-7
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https://doi.org/10.1186/s13578-024-01320-7

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